Title:
PEPTIDES AND PEPTIDE CONJUGATES FOR TREATING MENTAL DISORDERS
Document Type and Number:
WIPO Patent Application WO/2018/047852
Kind Code:
A1
Abstract:
Peptides, salts thereof, peptide conjugates, and salts thereof having 5 to 15 amino acids and having an amino acid sequence comprising at least 5 consecutive amino acids from the amino acid sequence LSSTQAQQSX1 (SEQ ID NO:34).
Inventors:
OHINATA KOUSAKU (JP)
MORI YUKIHA (JP)
SUZUKI HIDEYUKI (JP)
MORI YUKIHA (JP)
SUZUKI HIDEYUKI (JP)
Application Number:
PCT/JP2017/032079
Publication Date:
March 15, 2018
Filing Date:
September 06, 2017
Export Citation:
Assignee:
UNIV KYOTO (JP)
KAZUSA DNA RES INSTITUTE (JP)
KAZUSA DNA RES INSTITUTE (JP)
International Classes:
A61K38/10; A61K38/08; C07K7/06; C07K7/08
Domestic Patent References:
| WO2016140277A1 | 2016-09-09 |
Foreign References:
| US20100210564A1 | 2010-08-19 | |||
| EP2557088A1 | 2013-02-13 | |||
| JP2016056453W | 2016-03-02 |
Other References:
OTA AMI ET AL: "Rational identification of a novel soy-derived anxiolytic-like undecapeptide acting via gut-brain axis after oral administration.", NEUROCHEMISTRY INTERNATIONAL MAY 2017, vol. 105, May 2017 (2017-05-01), pages 51 - 57, XP002775557, ISSN: 1872-9754
MASAAKI YOSHIKAWA: "Bioactive peptides derived from natural proteins with respect to diversity of their receptors and physiological effects", PEPTIDES, vol. 72, 1 October 2015 (2015-10-01), AMSTERDAM, NL, pages 208 - 225, XP055424806, ISSN: 0196-9781, DOI: 10.1016/j.peptides.2015.07.013
TAKASHI NISHI ET AL: "The Soybean Beta-Conglycin Beta-51-63 Fragment Suppresses Appetite by Stimulating Cholecystokinin Release in Rats", THE JOURNAL OF NUTRITION, AMERICAN SOCIETY FOR NUTRITION, US, 1 January 2003 (2003-01-01), pages 2537 - 2542, XP002577476, ISSN: 0022-3166
YUKIHA MORI ET AL: "Characterization of soy-deprestatin, a novel orally-active decapeptide that exerts antidepressant-like effects via gut-brain communication", THE FASEB JOURNAL, 27 September 2017 (2017-09-27), US, XP055424793, ISSN: 0892-6638, DOI: 10.1096/fj.201700333RR
KESSLER ET AL., ARCH GEN PSYCHIATRY, vol. 62, no. 6, 2005, pages 617 - 627
WANG ET AL., ARCH GEN PSYCHIATRY, vol. 62, no. 6, 2005, pages 629 - 640
MARIN; WILKOSZ, J HEAD TRAUMA REHABIL, vol. 20, no. 4, 2005, pages 377 - 388
BONNELLE ET AL., JOURNAL OF PHYSIOLOGY, vol. 109, 2015, pages 16 - 26
"Handbook of Pharmaceutical Salts: Properties, Selection and Use", 2008, VERLAG HELVETICA CHIMICA ACTA
BENOITON, N.: "Chemistry of Peptide Synthesis", 2006, CRC PRESS
"Peptide Synthesis and Applications", 2005, HUMANA PRESS
"Fmoc Solid Phase Synthesis: A Practical Approach", 2000, OXFORD UNIVERSITY PRESS
HAMLEY, BIOMACROMOLECULES, vol. 15, 2014, pages 1543 - 1559
BASLE ET AL., CHEMISTRY & BIOLOGY, vol. 17, 2010, pages 213 - 227
"Modern Synthetic Methods", 1995, VERLAG HELVETICA CHIMICA ACTA
LUNDBLAD, R.: "Techniques in Protein Modification", 1995, CRC PRESS
"Remington: The Science and Practice of Pharmacy", 2012, PHARMACEUTICAL PRESS
CAN ET AL., J VIS EXP., vol. 59, 2012, pages e3769
CAN ET AL., J VIS EXP., vol. 59, 2012, pages e3638
KOMADA ET AL., J. VIS EXP., vol. 22, 2008, pages e1088
BAILEY; CRAWLEY: "Methods of Behavior Analysis in Neurscience", 2009, CRC PRESS, article "Anxiety-Related Behaviors in Mice"
MASAAKI YOSHIKAWA: "Bioactive peptides derived from natural proteins with respect to diversity of their receptors and physiological effects", PEPTIDES, vol. 72, 1 October 2015 (2015-10-01), AMSTERDAM, NL, pages 208 - 225, XP055424806, ISSN: 0196-9781, DOI: 10.1016/j.peptides.2015.07.013
TAKASHI NISHI ET AL: "The Soybean Beta-Conglycin Beta-51-63 Fragment Suppresses Appetite by Stimulating Cholecystokinin Release in Rats", THE JOURNAL OF NUTRITION, AMERICAN SOCIETY FOR NUTRITION, US, 1 January 2003 (2003-01-01), pages 2537 - 2542, XP002577476, ISSN: 0022-3166
YUKIHA MORI ET AL: "Characterization of soy-deprestatin, a novel orally-active decapeptide that exerts antidepressant-like effects via gut-brain communication", THE FASEB JOURNAL, 27 September 2017 (2017-09-27), US, XP055424793, ISSN: 0892-6638, DOI: 10.1096/fj.201700333RR
KESSLER ET AL., ARCH GEN PSYCHIATRY, vol. 62, no. 6, 2005, pages 617 - 627
WANG ET AL., ARCH GEN PSYCHIATRY, vol. 62, no. 6, 2005, pages 629 - 640
MARIN; WILKOSZ, J HEAD TRAUMA REHABIL, vol. 20, no. 4, 2005, pages 377 - 388
BONNELLE ET AL., JOURNAL OF PHYSIOLOGY, vol. 109, 2015, pages 16 - 26
"Handbook of Pharmaceutical Salts: Properties, Selection and Use", 2008, VERLAG HELVETICA CHIMICA ACTA
BENOITON, N.: "Chemistry of Peptide Synthesis", 2006, CRC PRESS
"Peptide Synthesis and Applications", 2005, HUMANA PRESS
"Fmoc Solid Phase Synthesis: A Practical Approach", 2000, OXFORD UNIVERSITY PRESS
HAMLEY, BIOMACROMOLECULES, vol. 15, 2014, pages 1543 - 1559
BASLE ET AL., CHEMISTRY & BIOLOGY, vol. 17, 2010, pages 213 - 227
"Modern Synthetic Methods", 1995, VERLAG HELVETICA CHIMICA ACTA
LUNDBLAD, R.: "Techniques in Protein Modification", 1995, CRC PRESS
"Remington: The Science and Practice of Pharmacy", 2012, PHARMACEUTICAL PRESS
CAN ET AL., J VIS EXP., vol. 59, 2012, pages e3769
CAN ET AL., J VIS EXP., vol. 59, 2012, pages e3638
KOMADA ET AL., J. VIS EXP., vol. 22, 2008, pages e1088
BAILEY; CRAWLEY: "Methods of Behavior Analysis in Neurscience", 2009, CRC PRESS, article "Anxiety-Related Behaviors in Mice"
Attorney, Agent or Firm:
SAEGUSA & PARTNERS (JP)
Download PDF:
Previous Patent: BATTERY UNIT AND VEHICULAR STORAGE BATTERY DEVICE
Next Patent: ORGANIC LIGHT-EMITTING DEVICE
Next Patent: ORGANIC LIGHT-EMITTING DEVICE