PEPTIDES FOR THE TREATMENT OF NEURODEGENERATIVE DISEASES

Title:

PEPTIDES FOR THE TREATMENT OF NEURODEGENERATIVE DISEASES

Document Type and Number:

WIPO Patent Application WO/2014/057484

Kind Code:

A8

Abstract:

An isolated peptide comprising a Huntingtin (Htt) amino acid sequence being no longer than 15 amino acids, wherein said Htt amino acid sequence comprises the sequence X1X2X3X4X5, wherein X1 is a hydrophobic amino acid or threonine, X2 is a hydrophobic amino acid, X3 is a hydrophobic amino acid, X4 is an acidic amino acid and X5 is selected from the group consisting of glycine, serine and alanine, the peptide capable of specifically inhibiting the activity of caspase 6.

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Inventors:

OFFEN DANIEL (IL)
AHARONY ISRAEL (IL)

Application Number:

PCT/IL2013/050196

Publication Date:

June 12, 2014

Filing Date:

March 05, 2013

Export Citation:

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Assignee:

UNIV RAMOT (IL)

International Classes:

C07K7/00; A61K38/04; A61K38/16; A61P25/00; C07K19/00

Attorney, Agent or Firm:

G. E. EHRLICH (1995) LTD. et al. (04 Ramat Gan, IL)

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