Title:
PET DEVICE WITH POSITRON LIFETIME MEASURING FUNCTION, AND METHOD FOR MEASURING POSITRON LIFETIME IN PET DEVICE
Document Type and Number:
WIPO Patent Application WO/2018/207739
Kind Code:
A1
Abstract:
A nuclide that emits positrons and then emits de-excited gamma rays is administered to an imaging target. A PET device detects the de-excited gamma rays separately from three annihilation gamma rays generated upon annihilation of positrons (ortho-positronium annihilation). On the basis of a detected energy (EDETγ1 to EDETγ3) and a detected position (PDETγ1 to PDETγ3) of each annihilation gamma ray, and a detection time (tDETγ1 to tDETγ3) of the annihilation gamma rays and a detection time (tDETγE) of the de-excited gamma rays, a distribution state of the nuclide in the imaging target is derived in three dimensions and is associated with a derived distribution position to determine lifetime information of the positrons.
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Inventors:
FUKUCHI TOMONORI (JP)
Application Number:
PCT/JP2018/017657
Publication Date:
November 15, 2018
Filing Date:
May 07, 2018
Export Citation:
Assignee:
RIKEN (JP)
International Classes:
G01T1/161
Foreign References:
| JP5526435B2 | 2014-06-18 | |||
| JPS5526435B1 | 1980-07-12 |
Other References:
KACPERSKI, KRZYSZTOF ET AL.: "Three-Gamma Annihilations as a New Modality in PET", IEEE SYMPOSIUM CONFERENCE RECORD NUCLEAR SCIENCE 2004, 1 August 2005 (2005-08-01), pages 3752 - 3756, XP010819506
SAITO HARUO ET AL.: "Positron lifetime measurement technique", POSITRON SCIENCES, vol. 2, 2014, pages 21 - 27, XP055643246
FUKUCHI, TOMONORI ET AL.: "Positrion emission tomograhy with additional gamma-ray detectors for multiple-traver imaging", MEDICAL PHYSICS, vol. 44, no. 6, 7 February 2017 (2017-02-07), pages 2257 - 2266, XP055563253
ABUELHIA, ELFAITH ET AL.: "Three-photon annihilation in PET:2D imaging experiments", JOURNAL OF RADIOANALYTICAL AND NUCLEAR CHEMISTRY, vol. 271, no. 2, 2007, pages 489 - 495, XP019452225
See also references of EP 3623847A4
A. ANDREYEVA. CELLER: "Dual-isotope PET using positron-gamma emitters", PHYSICS IN MEDICAL AND BIOLOGY, vol. 56, 2011, pages 4539 - 4556
R. B. BELLR. L. GRAHAM: "Time Distribution of Positron Annihilation in Liquids and Solids", PHYS. REV., vol. 90, 1953, pages 644 - 654
"Principles and Applications of Positron and Positronium Chemistry", 2003, WORLD SCIENTIFIC
A. M. COOPERG. J. LAIDLAWB. G. HOGG: "Oxygen quenching of positron lifetimes in liquids", J. CHEM. PHYS., vol. 46, 1967, pages 2441 - 2442
B. HOPKINST. W. ZERDA: "Oxygen quenching of positronium in silica gels", PHYS. LETT., vol. A45, 1990, pages 141 - 145, XP024505115, DOI: 10.1016/0375-9601(90)90207-5
M. D. HARPEN: "Positronium: Review of symmetry, conserved quantities and decay for the radiological physicist", MEDICAL PHYSICS, vol. 31, no. 1, 2004, pages 57 - 61, XP012074752, DOI: 10.1118/1.1630494
K. KACPERSKIM. N. SPYROU: "Performance of three-photon PET imaging: Monte Carlo simulations", PHYS. MED. BIOL., vol. 50, 2005, pages 5679 - 5696
SAITO HARUO ET AL.: "Positron lifetime measurement technique", POSITRON SCIENCES, vol. 2, 2014, pages 21 - 27, XP055643246
FUKUCHI, TOMONORI ET AL.: "Positrion emission tomograhy with additional gamma-ray detectors for multiple-traver imaging", MEDICAL PHYSICS, vol. 44, no. 6, 7 February 2017 (2017-02-07), pages 2257 - 2266, XP055563253
ABUELHIA, ELFAITH ET AL.: "Three-photon annihilation in PET:2D imaging experiments", JOURNAL OF RADIOANALYTICAL AND NUCLEAR CHEMISTRY, vol. 271, no. 2, 2007, pages 489 - 495, XP019452225
See also references of EP 3623847A4
A. ANDREYEVA. CELLER: "Dual-isotope PET using positron-gamma emitters", PHYSICS IN MEDICAL AND BIOLOGY, vol. 56, 2011, pages 4539 - 4556
R. B. BELLR. L. GRAHAM: "Time Distribution of Positron Annihilation in Liquids and Solids", PHYS. REV., vol. 90, 1953, pages 644 - 654
"Principles and Applications of Positron and Positronium Chemistry", 2003, WORLD SCIENTIFIC
A. M. COOPERG. J. LAIDLAWB. G. HOGG: "Oxygen quenching of positron lifetimes in liquids", J. CHEM. PHYS., vol. 46, 1967, pages 2441 - 2442
B. HOPKINST. W. ZERDA: "Oxygen quenching of positronium in silica gels", PHYS. LETT., vol. A45, 1990, pages 141 - 145, XP024505115, DOI: 10.1016/0375-9601(90)90207-5
M. D. HARPEN: "Positronium: Review of symmetry, conserved quantities and decay for the radiological physicist", MEDICAL PHYSICS, vol. 31, no. 1, 2004, pages 57 - 61, XP012074752, DOI: 10.1118/1.1630494
K. KACPERSKIM. N. SPYROU: "Performance of three-photon PET imaging: Monte Carlo simulations", PHYS. MED. BIOL., vol. 50, 2005, pages 5679 - 5696
Attorney, Agent or Firm:
SANO PATENT OFFICE (JP)
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