Title:
PH-RESPONSIVE ANALGESIC AGENT FOR TARGETING DAMAGED SEGMENT DORSAL ROOT GANGLION AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2023/143261
Kind Code:
A1
Abstract:
A pH-responsive analgesic agent for targeting a damaged segment dorsal root ganglion and use thereof. A pH-responsive carrier is adopted to embed an opioid analgesic agent to prepare a peripheral nerve damage analgesic agent; the damaged segment dorsal root ganglion is taken as a drug target, such that the analgesic agent is continuously and slowly released at the dorsal root ganglion site of the damaged segment.
Inventors:
TANG JIANBIN (CN)
YAN MIN (CN)
MA LONGFEI (CN)
YUAN PENGCHENG (CN)
YU LINA (CN)
YAN MIN (CN)
MA LONGFEI (CN)
YUAN PENGCHENG (CN)
YU LINA (CN)
Application Number:
PCT/CN2023/072651
Publication Date:
August 03, 2023
Filing Date:
January 17, 2023
Export Citation:
Assignee:
UNIV ZHEJIANG (CN)
International Classes:
A61K45/00; A61K9/127; A61K31/4468; A61K31/4535; A61K31/454; A61K31/485; A61K47/12; A61K47/24; A61P25/02; A61P25/04; A61P29/00
Foreign References:
| CN114949220A | 2022-08-30 | |||
| CN102164588A | 2011-08-24 | |||
| US20140228406A1 | 2014-08-14 | |||
| US5451408A | 1995-09-19 |
Other References:
XUE, DAQUAN ET AL.: "Research Progress of Liposome", NEW TECHNOLOGY OF PHARMACEUTICAL PREPARATIONS AND NEW DRUG RESEARCH AND DEVELOPMENT, 31 May 2016 (2016-05-31), XP009548344
Attorney, Agent or Firm:
HANGZHOU TIANQIN INTELLECTUAL PROPERTY AGENCY CO., LTD. (CN)
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