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Title:
PHARMACEUTICAL COMPOSITION COMPRISING APIGENIN, CURCUMIN, AND HONOKIOL AS ACTIVE INGREDIENTS FOR PREVENTING OR TREATING LUNG CANCER
Document Type and Number:
WIPO Patent Application WO/2018/043989
Kind Code:
A1
Abstract:
The present invention relates to a pharmaceutical composition comprising, as active ingredients, apigenin or curcumin, and honokiol for preventing or treating lung cancer. In the composition according to the present invention, when compared with the treatment with apigenin, curcumin, or honokiol alone, the treatment with a mixture or combination thereof synergistically induces the apoptosis of cancer cells, and thus the pharmaceutical composition comprising, as active ingredients, apigenin or curcumin, and honokiol for preventing or treating lung cancer of the present invention increases an anticancer effect to induce the apoptosis of cancer cells, thereby exhibiting an excellent cancer treatment increasing effect. Therefore, the composition according to the present invention can be advantageously used in the prevention, alleviation, or treatment of lung cancer.

Inventors:
KIM, Chul-Woo (22-402, 637 Achasan-ro,Gwangjin-gu, Seoul, 04964, KR)
JANG, Ji-Young (110-701, 197 Seoun-ro,Seocho-gu, Seoul, 06608, KR)
Application Number:
KR2017/009241
Publication Date:
March 08, 2018
Filing Date:
August 24, 2017
Export Citation:
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Assignee:
BIOINFRA LIFE SCIENCE INC. (7th Floor, 49 Daehak-ro,,Jongno-gu, Seoul, 03127, KR)
International Classes:
A61K31/352; A23L33/10; A61K31/05; A61K31/12
Domestic Patent References:
WO2012159085A22012-11-22
Foreign References:
US20160129127A12016-05-12
US20160015709A12016-01-21
US8916541B22014-12-23
US20060189680A12006-08-24
Attorney, Agent or Firm:
LEE, Myoung-Jin (6th floor, 28 Yeongdong-daero 85-gil,Gangnam-gu, Seoul, 06180, KR)
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