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Title:
PHARMACEUTICAL COMPOSITION COMPRISING NITROGENATED FUSED CYCLIC COMPOUND
Document Type and Number:
WIPO Patent Application WO/2007/138998
Kind Code:
A1
Abstract:
Disclosed is a pharmaceutical composition which is effective for the treatment or prevention of a disease associated with uric acid, such as hyperuricemia, tophus, acute gouty arthritis, chronic gouty arthritis, gouty kidney, urinary calculus, renal dysfunction, coronary disorder and ischemic heart disease, and which has excellent long-term stability and elution properties (disintegration properties). The pharmaceutical composition comprises a nitrogenated fused cyclic compound represented by the general formula [1] or a pharmaceutically acceptable salt thereof and at least one pharmaceutically acceptable additive, wherein the nitrogenated fused cyclic compound or the pharmaceutically acceptable salt thereof is not contacted with a basic additive. [1] wherein each symbol is as defined in the description.

Inventors:
MIKI KAZUKI (JP)
ARIMOTO FUYUKI (JP)
SUNAMI MASAKI (JP)
Application Number:
PCT/JP2007/060672
Publication Date:
December 06, 2007
Filing Date:
May 25, 2007
Export Citation:
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Assignee:
JAPAN TOBACCO INC (JP)
MIKI KAZUKI (JP)
ARIMOTO FUYUKI (JP)
SUNAMI MASAKI (JP)
International Classes:
A61K31/538; A61K9/20; A61K9/28; A61K9/36; A61K31/404; A61K31/47; A61K31/498; A61K31/5383; A61K31/5415; A61K31/55; A61K31/5513; A61K31/553; A61K47/02; A61K47/04; A61K47/10; A61K47/12; A61K47/26; A61K47/32; A61K47/34; A61K47/36; A61K47/38; A61P9/10; A61P13/02; A61P13/12; A61P19/02; A61P19/06; A61P43/00; C07D209/08; C07D215/08; C07D223/16; C07D241/12; C07D243/12; C07D265/36; C07D267/14; C07D279/16; C07D413/06; C07D498/04
Domestic Patent References:
WO2006057460A12006-06-01
WO2004085401A12004-10-07
Foreign References:
JPH04321669A1992-11-11
JPH08301848A1996-11-19
JPH072800A1995-01-06
JP2002513425A2002-05-08
Other References:
JAPAN PHARMACEUTICAL EXCIPIENTS COUNCIL: "Iyakuhin Tenkabutsu Jiten", vol. 1ST ED., 14 January 1994, KABUSHIKI KAISHA YAKUJI NIPPOSHA, XP003019723
Attorney, Agent or Firm:
TAKASHIMA, Hajime (1-1 Fushimimachi 4-chome, Chuo-ku,Osaka-sh, Osaka 44, JP)
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