Title:
PHARMACEUTICAL COMPOSITION COMPRISING A TRIPLE-ACTIVATOR PERSISTENT CONJUGATE AS ACTIVE INGREDIENT
Document Type and Number:
WIPO Patent Application WO/2022/035271
Kind Code:
A1
Abstract:
The present invention relates to a pharmaceutical composition comprising a triple-activator persistent conjugate as an active ingredient and a method for treating obesity and/or nonalcoholic steatohepatitis disease by using same. The composition comprising a persistent conjugate of a triple activator according to the present invention can be applied to the treatment of obesity and/or nonalcoholic steatohepatitis disease without adverse effects according to the stability and therapeutic efficacy for obesity and/or nonalcoholic steatohepatitis disease.
Inventors:
BAEK SEUNGJAE (KR)
CHOI JAEDUK (KR)
SHIN WONJUNG (KR)
KIM JUNG KUK (KR)
CHOI JAEDUK (KR)
SHIN WONJUNG (KR)
KIM JUNG KUK (KR)
Application Number:
PCT/KR2021/010780
Publication Date:
February 17, 2022
Filing Date:
August 13, 2021
Export Citation:
Assignee:
HANMI PHARM IND CO LTD (KR)
International Classes:
A61K47/68; A61K9/00; A61K38/17; A61K38/22; A61K38/26; A61K47/54; A61K47/60; A61P1/16
Domestic Patent References:
| WO2015067716A1 | 2015-05-14 | |||
| WO2017116204A1 | 2017-07-06 | |||
| WO2017116205A1 | 2017-07-06 | |||
| WO1997034631A1 | 1997-09-25 | |||
| WO1996032478A1 | 1996-10-17 |
Foreign References:
| KR20170080522A | 2017-07-10 | |||
| KR20200088418A | 2020-07-22 | |||
| JP2015521622A | 2015-07-30 | |||
| US20140018291A1 | 2014-01-16 |
Other References:
HEPATOLOGY, vol. 38, 2003, pages 1008 - 17
J CLIN INVEST., vol. 108, 2001, pages 1167 - 74
PEARSON ET AL., PROC. NATL. ACAD. SCI. USA, vol. 85, 1988, pages 2444
"Needleman-Wunsch algorithm", J. MOL. BIOL., vol. 48, 1970, pages 443 - 453
RICE ET AL., TRENDS GENET, vol. 16, 2000, pages 276 - 277
DEVEREUX, J. ET AL., NUCLEIC ACIDS RESEARCH, vol. 12, 1984, pages 387
ATSCHUL, S. F. ET AL., J MOLEC BIOL, vol. 215, 1990, pages 403
"Guide to Huge Computers", 1994, ACADEMIC PRESS
CARILLO ET AL., SIAM J APPLIED MATH, vol. 48, 1988, pages 1073
NEEDLEMAN ET AL., J MOL BIOL., vol. 48, 1970, pages 443
SMITHWATERMAN, ADV. APPL. MATH, vol. 2, 1981, pages 482
H. NEURATHR. L. HILL: "The Proteins", 1979, ACADEMIC PRESS
J CLIN INVEST., vol. 108, 2001, pages 1167 - 74
PEARSON ET AL., PROC. NATL. ACAD. SCI. USA, vol. 85, 1988, pages 2444
"Needleman-Wunsch algorithm", J. MOL. BIOL., vol. 48, 1970, pages 443 - 453
RICE ET AL., TRENDS GENET, vol. 16, 2000, pages 276 - 277
DEVEREUX, J. ET AL., NUCLEIC ACIDS RESEARCH, vol. 12, 1984, pages 387
ATSCHUL, S. F. ET AL., J MOLEC BIOL, vol. 215, 1990, pages 403
"Guide to Huge Computers", 1994, ACADEMIC PRESS
CARILLO ET AL., SIAM J APPLIED MATH, vol. 48, 1988, pages 1073
NEEDLEMAN ET AL., J MOL BIOL., vol. 48, 1970, pages 443
SMITHWATERMAN, ADV. APPL. MATH, vol. 2, 1981, pages 482
H. NEURATHR. L. HILL: "The Proteins", 1979, ACADEMIC PRESS
Attorney, Agent or Firm:
HANOL INTELLECTUAL PROPERTY AND LAW (KR)
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