Title:
PHARMACEUTICAL COMPOSITION CONTAINING AMLODIPINE, CHLORTHALIDONE, AND AMILORIDE
Document Type and Number:
WIPO Patent Application WO/2020/207355
Kind Code:
A1
Abstract:
Provided is a pharmaceutical composition for treating refractory hypertension. The pharmaceutical composition consists of amlodipine, chlorthalidone, and amiloride. The provided pharmaceutical composition provides an effective antihypertensive drug for patients with refractory hypertension, especially refractory hypertension patients with low renin/low aldosterone, and the provided pharmaceutical composition can also enhance the protective effect on the target organs of patients with refractory hypertension and reduce the risk of cerebrovascular events.
Inventors:
CHEN GUANGLIANG (CN)
YU DUO (CN)
BAI JIE (CN)
TIAN MINQING (CN)
CHEN PING (CN)
XU XIPING (CN)
YU DUO (CN)
BAI JIE (CN)
TIAN MINQING (CN)
CHEN PING (CN)
XU XIPING (CN)
Application Number:
PCT/CN2020/083332
Publication Date:
October 15, 2020
Filing Date:
April 03, 2020
Export Citation:
Assignee:
SHENZHEN AUSA PHARMED CO LTD (CN)
SHENZHEN AUSA PHARMACEUTICAL CO LTD (CN)
SHENZHEN AUSA PHARMACEUTICAL CO LTD (CN)
International Classes:
A61K31/4965; A61K31/4035; A61K31/4422; A61P7/04; A61P9/00; A61P9/10; A61P9/12; A61P13/12
Domestic Patent References:
| WO2007075542A2 | 2007-07-05 |
Foreign References:
| CN101890166A | 2010-11-24 | |||
| CN1342091A | 2002-03-27 | |||
| CN110545819A | 2019-12-06 | |||
| CN101730694A | 2010-06-09 |
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