Title:
PHARMACEUTICAL COMPOSITION CONTAINING BURDOCK ROOT EXTRACT AS ACTIVE INGREDIENT FOR PREVENTING OR TREATING DIABETIC COMPLICATIONS
Document Type and Number:
WIPO Patent Application WO/2018/043852
Kind Code:
A1
Abstract:
The present invention relates to a composition containing a burdock root extract as an active ingredient for preventing or treating diabetic complications. More specifically, a burdock root extract was confirmed to exhibited an effect of inhibiting the production of advanced glycation end products (AGEs), shown in a non-enzymatic glycation reaction by the sugar in the blood, and thus a composition containing the burdock root extract as an active ingredient can be provided as a pharmaceutical composition or health food for preventing and treating diabetic complications caused by advanced glycation end products (AGEs).
Inventors:
KIM CHOON YOUNG (KR)
Application Number:
PCT/KR2017/002397
Publication Date:
March 08, 2018
Filing Date:
March 06, 2017
Export Citation:
Assignee:
UNIV YEUNGNAM RES COOPERATION FOUNDATION (KR)
International Classes:
A61K36/28; A23L33/105
Other References:
CAO, J. ET AL.: "Antidiabetic Effect of Burdock (Arctium lappa L.) Root Ethanolic Extract on Streptozotocin-induced Diabetic Rats", AFRICAN JOURNAL OF BIOTECHNOLOGY, vol. 11, no. 37, 2012, pages 9079 - 9085, XP055471781
KWON, YU-RI ET AL.: "Physicochemical of Burdock (Arctium lappa L.) Tea Depending on Steaming and Roasting Treatment", THE KOREAN SOCIETY OF FOOD PRESERVATION, vol. 21, no. 5, 2014, pages 646 - 651, XP053034151
SINGH , V. P. ET AL.: "Advanced Glycation End Products and Diabetic Complications", THE KOREAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY, vol. 18, 2014
WANG, Z. ET AL.: "Protective Effects of Arctium lappa L. Root Extracts (AREs) on High Fat Diet Induced Quail Atherosclerosis", BMC COMPLEMENTARY AND ALTERNATIVE MEDICINE, vol. 16, no. 6, 8 January 2016 (2016-01-08), pages 1 - 1 1, XP021249226
LI. S.-Y. ET AL.: "High-fat Diet Enhances Visceral Advanced Glycation End Products, Nuclear O-Glc-Nac Modification, p38 Mitogen-activated Protein Kinase Activation and Apoptosis", DIABETES, OBESITY AND METABOLISM, vol. 7, 2005, pages 448 - 454, XP002512626
LEE, DA RYE ET AL.: "Inhibition of Advanced Glycation End Product Formation by Burdock Root Extract", THE KOREAN NUTRITION SOCIETY, vol. 49, no. 4, 31 August 2016 (2016-08-31), pages 233 - 240, XP053035206
KWON, YU-RI ET AL.: "Physicochemical of Burdock (Arctium lappa L.) Tea Depending on Steaming and Roasting Treatment", THE KOREAN SOCIETY OF FOOD PRESERVATION, vol. 21, no. 5, 2014, pages 646 - 651, XP053034151
SINGH , V. P. ET AL.: "Advanced Glycation End Products and Diabetic Complications", THE KOREAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY, vol. 18, 2014
WANG, Z. ET AL.: "Protective Effects of Arctium lappa L. Root Extracts (AREs) on High Fat Diet Induced Quail Atherosclerosis", BMC COMPLEMENTARY AND ALTERNATIVE MEDICINE, vol. 16, no. 6, 8 January 2016 (2016-01-08), pages 1 - 1 1, XP021249226
LI. S.-Y. ET AL.: "High-fat Diet Enhances Visceral Advanced Glycation End Products, Nuclear O-Glc-Nac Modification, p38 Mitogen-activated Protein Kinase Activation and Apoptosis", DIABETES, OBESITY AND METABOLISM, vol. 7, 2005, pages 448 - 454, XP002512626
LEE, DA RYE ET AL.: "Inhibition of Advanced Glycation End Product Formation by Burdock Root Extract", THE KOREAN NUTRITION SOCIETY, vol. 49, no. 4, 31 August 2016 (2016-08-31), pages 233 - 240, XP053035206
Attorney, Agent or Firm:
TAEBAEK INTELLECTUAL PROPERTY LAW FIRM (KR)
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