Title:
PHARMACEUTICAL COMPOSITION CONTAINING HDAC6 INHIBITOR AS ACTIVE INGREDIENT FOR PREVENTION OR TREATMENT OF ITCHING
Document Type and Number:
WIPO Patent Application WO/2019/139244
Kind Code:
A1
Abstract:
The present invention relates to a pharmaceutical composition containing an HDAC6 inhibitor as an active ingredient for prevention or treatment of itching. The present invention provides a novel pharmaceutical composition containing, as an active ingredient, an inhibitor for inhibiting an HDAC6 enzyme, and thus can effectively inhibit and treat itching caused by trypsin, tryptase, histamine, antimycin A, chloroquine, or the like.
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Inventors:
JANG JUN HO (KR)
YOON JEONG AH (KR)
YOON JEONG AH (KR)
Application Number:
PCT/KR2018/014029
Publication Date:
July 18, 2019
Filing Date:
November 15, 2018
Export Citation:
Assignee:
BNH RES CO LTD (KR)
International Classes:
A61K31/437; A61K31/422; A61P17/00; A61P17/04
Foreign References:
| EP2033635A1 | 2009-03-11 | |||
| US8846039B2 | 2014-09-30 | |||
| JP2009051777A | 2009-03-12 | |||
| KR20170013186A | 2017-02-06 |
Other References:
ZAIN, JASMINE: "Targeting histone deacetyalses in the treatment of B- and T- cell malignancies", INVEST NEW DRUGS, vol. 28, no. 1, 2010, pages S58 - S78, XP019869089
CEDENO-LAURENT FILIBERTO: "Improved pruritus correlates with lower levels of IL -31 in CTCL patients under different therapeutic modalities", CLINICAL IMMUNOLOGY, vol. 158, no. 1, 2015, pages 1 - 7, XP055625026
CEDENO-LAURENT FILIBERTO: "Improved pruritus correlates with lower levels of IL -31 in CTCL patients under different therapeutic modalities", CLINICAL IMMUNOLOGY, vol. 158, no. 1, 2015, pages 1 - 7, XP055625026
Attorney, Agent or Firm:
HAEUM PATENT & LAW FIRM (KR)
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