Title:
PHARMACEUTICAL COMPOSITION AND DOSAGE FORM CONTAINING GLAUCOCALYXIN A DERIVATIVE OR SALT THEREOF
Document Type and Number:
WIPO Patent Application WO/2016/150208
Kind Code:
A1
Abstract:
Disclosed are a pharmaceutical composition and dosage form containing a glaucocalyxin A derivative as represented by the formula (I) or salt thereof, and a preparation method and use of said composition and dosage form; the anti-autoimmunity and antitumor effects of the pharmaceutical composition and dosage form of the glaucocalyxin A derivative or salt thereof, provided by the present invention, are highly pertinent and may be used for further development of new pharmaceutical formulations for chemotherapy treatment of autoimmune diseases and treatment of cancer diseases, and are expected to supplement pharmaceutical blanks for treating such difficult-to-treat diseases as systemic lupus erythematosus, psoriasis, and triple-negative breast cancer.
Inventors:
LI YUNSEN (CN)
CHEN ZIJUN (CN)
DENG SHIPING (CN)
FENG HAIMEI (CN)
LIU QIAN (CN)
LI YONG (CN)
CHEN XIANG (CN)
CHEN ZIJUN (CN)
DENG SHIPING (CN)
FENG HAIMEI (CN)
LIU QIAN (CN)
LI YONG (CN)
CHEN XIANG (CN)
Application Number:
PCT/CN2015/097693
Publication Date:
September 29, 2016
Filing Date:
December 17, 2015
Export Citation:
Assignee:
SUZHOU PHARMAVAN CANCER RES CENTER CO LTD (CN)
International Classes:
C07C225/12; A61K31/133; A61P35/00; A61P37/00; C07C221/00; C07C225/20; C07C237/30; C07D207/325; C07D233/60; C07D295/116
Foreign References:
| CN101914002A | 2010-12-15 | |||
| CN104817464A | 2015-08-05 | |||
| CN104887652A | 2015-09-09 | |||
| CN104761460A | 2015-07-08 |
Other References:
YANG JINGET ET AL.: "Synthesis And Biological Evaluation of Glaucocalyxin A Derivatives as Potential Anticancer Agents", EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, vol. 86, 21 August 2014 (2014-08-21), pages 235 - 241, XP029048580, ISSN: 0223-5234
YANG, JINGET ET AL.: "Synthesis And Biological Evaluation of Glaucocalyxin A Derivatives as Potential Anticancer Agents", EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, vol. 86, 21 August 2014 (2014-08-21), pages 235 - 241, XP029048580, ISSN: 0223-5234
ZHU, SHENGSHAN.: "Chapter Two Adjuvant Selection and Compatibility of Pharmaceutical Preparation", PHARMACEUTICAL PREPARATION ENGINEERING, 31 August 2002 (2002-08-31), pages 7 - 12
YANG, JINGET ET AL.: "Synthesis And Biological Evaluation of Glaucocalyxin A Derivatives as Potential Anticancer Agents", EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, vol. 86, 21 August 2014 (2014-08-21), pages 235 - 241, XP029048580, ISSN: 0223-5234
ZHU, SHENGSHAN.: "Chapter Two Adjuvant Selection and Compatibility of Pharmaceutical Preparation", PHARMACEUTICAL PREPARATION ENGINEERING, 31 August 2002 (2002-08-31), pages 7 - 12
Attorney, Agent or Firm:
BEYOND ATTORNEYS AT LAW (CN)
北京品源专利代理有限公司 (CN)
北京品源专利代理有限公司 (CN)
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