Title:
PHARMACEUTICAL COMPOSITION AND METHOD FOR TREATMENT OF BRAIN INJURY, SPINAL CORD INJURY, STROKE, NEURODEGENERATIVE DISEASE AND OTHER CONDITIONS
Document Type and Number:
WIPO Patent Application WO2002043654
Kind Code:
A8
Abstract:
Disclosed is a pharmaceutical composition comprising a substance that upon administration to a patient leads to an inhibition of extension of cellular processes of astrocytes and/or a retraction of said cellular processes. Disclosed is also use of said substance for the production of a pharmaceutical composition for treatment of a condition selected from the group consisting of brain injury, spinal cord injury, stroke, neurodegenerative diseases, neuronal and/or synaptic loss associated with ageing, disorders of the brain associated with ageing and diabetic retinopathy, and also a method for treatment of said conditions wherein said substance is administered to a patient. Examples of such substances are quercetin, endothelin, hyaluronectin, L2 antibody, L2 glycolipid, L2 tetrasaccharide, TGF-alpha, or a tyrosine phosphatase inhibitor such as orthovanadate or phenylarsine oxide.
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Inventors:
PEKNY MILOS (SE)
Application Number:
PCT/SE2001/002656
Publication Date:
April 01, 2004
Filing Date:
November 30, 2001
Export Citation:
Assignee:
PEKNY MILOS (SE)
International Classes:
A61K31/00; A61K31/352; A61K38/18; A61K38/22; A61P25/00; A61P25/28; C12N15/12; (IPC1-7): A61K31/00; A61K38/00; A61P25/28
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