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Title:
PHARMACEUTICAL COMPOSITION AND METHOD FOR TREATMENT OR PREVENTION OF CANCER
Document Type and Number:
WIPO Patent Application WO/2023/017836
Kind Code:
A1
Abstract:
THE present invention includes a pharmaceutical composition for the treatment or prevention of cancer in HLA-A*11:01-, HLA-A*02:01-, HLA-A*02:06-, HLA-A*02:07-, HLA-A*26:01-, HLA-A*26:03-, HLA-A*01:01-, HLA-B*15:01-, HLA-B*35:01-, HLA-C*03:03-, HLA-C*05-01-, HLA-C*07:01-, or HLA-C*07:02-positive subjects. The pharmaceutical composition includes a peptide that comprises an amino acid sequence of WAPVLDFAPPGASAYGSL (SEQ ID NO: 2), a modified peptide thereof that is CTL-inducing, or a pharmacologically acceptable salt thereof.

Inventors:
KOIDO SHIGEO (JP)
SUGIYAMA HARUO (JP)
Application Number:
PCT/JP2022/030546
Publication Date:
February 16, 2023
Filing Date:
August 10, 2022
Export Citation:
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Assignee:
INT INST CANCER IMMUNOLOGY INC (JP)
International Classes:
A61K39/00; A61P35/00; A61P35/02; A61P43/00; C07K7/08
Domestic Patent References:
WO2020204173A12020-10-08
WO2020204172A12020-10-08
WO2019131722A12019-07-04
WO2010123065A12010-10-28
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WO2000018795A22000-04-06
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Foreign References:
JP2021131636A2021-09-09
Other References:
INT. J. CANCER, vol. 100, 2002, pages 565 - 570
NAT. MED., vol. 4, 1998, pages 321 - 327
CANCER IMMUNOL. IMMUNOTHER., vol. 51, 2002, pages 271
"Peptide Synthesis", vol. 14, 1991, HIROKAWA SHOTEN, article "Development of Pharmaceutical Product sequential"
"The Proteins", vol. 2, 1976, ACADEMIC PRESS INC.
"peptide synthesis", 1975, MARUZEN CO., LTD.
DM. GLOVER: "Basics and Experiment of peptide synthesis", 1985, MARUZEN CO., LTD.
T. MANIATIS ET AL.: "Molecular Cloning", 1983, CSH LABORATORY
CLIN. MICROBIOL. REV., vol. 7, 1994, pages 277 - 289
Attorney, Agent or Firm:
YAMAO, Norihito et al. (JP)
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