Title:
PHARMACEUTICAL COMPOSITION FOR ORAL ADMINISTRATION
Document Type and Number:
WIPO Patent Application WO/2020/045607
Kind Code:
A1
Abstract:
Provided is a stable pharmaceutical composition for oral administration that exhibits rapid drug elution in a pharmaceutical composition for oral administration containing 6-(4,4-dimethylcyclohexyl)-4-[(1,1-dioxo-1λ6-thiomorpholin-4-yl)methyl]-2-methylthieno[2,3-d]pyrimidine or a pharmacologically acceptable salt thereof. The pharmaceutical composition for oral administration contains a water-swellable substance, and the water-swellable substance is a polymer compound obtained by condensation polymerization of β-glucose, a polymer compound obtained by condensation polymerization of α-glucose, or a polymer compound having a pyrrolidone functional group.
Inventors:
KOJIMA RYO (JP)
SAKAI TOSHIRO (JP)
AZUMA RYOTA (JP)
TANAKA MARINA (JP)
SAKAI TOSHIRO (JP)
AZUMA RYOTA (JP)
TANAKA MARINA (JP)
Application Number:
PCT/JP2019/034051
Publication Date:
March 05, 2020
Filing Date:
August 30, 2019
Export Citation:
Assignee:
ASTELLAS PHARMA INC (JP)
International Classes:
A61K31/519; A61K9/14; A61K9/20; A61K9/48; A61K47/32; A61K47/38; A61P21/02; A61P25/04; A61P25/08; A61P25/18; A61P25/28; A61P29/02; A61P43/00
Domestic Patent References:
| WO2015056771A1 | 2015-04-23 | |||
| WO2015056771A1 | 2015-04-23 |
Foreign References:
| JP2016538256A | 2016-12-08 | |||
| JPS58134033A | 1983-08-10 |
Other References:
TAGAWA MAYA ET AL.: "Effective of various Disintegrants on Drug Release Behavior from Tabl", JOURNAL OF PHARMACEUTICAL SCIENCE AND TECHNOLOGY, JAPAN, vol. 63, no. 4, 11 August 2003 (2003-08-11), pages 238 - 248, XP003019852
"Dissolution Test of the Japanese Pharmacopoeia"
See also references of EP 3845230A4
"Dissolution Test of the Japanese Pharmacopoeia"
See also references of EP 3845230A4
Attorney, Agent or Firm:
YAMAGUCHI Kenjiro et al. (JP)
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