Title:
PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING AUTOPHAGY-RELATED DISEASES, ANGIOGENIC DISEASES OR MELANIN-RELATED DISEASES
Document Type and Number:
WIPO Patent Application WO/2012/074187
Kind Code:
A1
Abstract:
The present invention relates to a pharmaceutical composition for preventing or treating autophagy-related diseases, angiogenic diseases or hypermelanosis, comprising: (a) a pharmaceutically effective amount of an indatraline derivative or a pharmaceutically acceptable salt thereof; and a pharmaceutically acceptable carrier. The composition of the present invention effectively induces autophagy of cells, and thus is very effective for preventing or treating autophagy-related diseases. In addition, the composition of the present invention inhibits angiogenesis through the mechanism of inhibiting angiogenesis, invasion and metastasis and inhibits melanogenesis, and thus can also be effective for preventing or treating angiogenic diseases or melanin-related diseases.
Inventors:
KWON HO JEONG (KR)
CHO YOON SUN (KR)
CHO YOON SUN (KR)
Application Number:
PCT/KR2011/006581
Publication Date:
June 07, 2012
Filing Date:
September 06, 2011
Export Citation:
Assignee:
UNIV YONSEI IACF (KR)
KWON HO JEONG (KR)
CHO YOON SUN (KR)
KWON HO JEONG (KR)
CHO YOON SUN (KR)
International Classes:
A61K31/04; A61K31/015; A61P9/00; A61P17/00
Domestic Patent References:
| WO1998006689A1 | 1998-02-19 | |||
| WO2009036275A1 | 2009-03-19 |
Foreign References:
| US20090076019A1 | 2009-03-19 |
Attorney, Agent or Firm:
YANG, Boo-Hyun (1659-2 Inhundong Gwanak-gu, Seoul 151-832, KR)
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