Title:
PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING DIABETES COMPLICATIONS COMPRISING NOVEL CHRYSIN DERIVATIVE COMPOUND AS ACTIVE INGREDIENT
Document Type and Number:
WIPO Patent Application WO/2019/151732
Kind Code:
A1
Abstract:
The present invention relates to a pharmaceutical composition for preventing or treating diabetes complications comprising a novel chrysin derivative compound as an active ingredient and, more specifically, to a pharmaceutical composition for preventing or treating diabetes complications comprising, as an active ingredient, a novel chrysin derivative compound which has an effect of inhibiting the formation of an advanced glycation end product (AGE) and can, thereby, prevent or treat diabetes complications.
Inventors:
LIM SOON SUNG (KR)
HWANG SEUNG HWAN (KR)
LEE SOO KYEONG (KR)
ZUO GUANG LEI (KR)
KWON JEONG HAN (KR)
HAN JONG WOO (KR)
HAN BOK NAM (KR)
LEE JI YEON (KR)
PARK KYEONG HEE (KR)
LEE HYUN KYUNG (KR)
SA YUN JI (KR)
LEE JI HYUN (KR)
HWANG SEUNG HWAN (KR)
LEE SOO KYEONG (KR)
ZUO GUANG LEI (KR)
KWON JEONG HAN (KR)
HAN JONG WOO (KR)
HAN BOK NAM (KR)
LEE JI YEON (KR)
PARK KYEONG HEE (KR)
LEE HYUN KYUNG (KR)
SA YUN JI (KR)
LEE JI HYUN (KR)
Application Number:
PCT/KR2019/001158
Publication Date:
August 08, 2019
Filing Date:
January 28, 2019
Export Citation:
Assignee:
UNIV HALLYM IACF (KR)
International Classes:
A61K31/353; A61K9/00; A61P3/10
Domestic Patent References:
| WO2008008033A1 | 2008-01-17 |
Foreign References:
| KR20170002565A | 2017-01-06 | |||
| KR101742096B1 | 2017-06-15 | |||
| KR101510257B1 | 2015-04-09 |
Other References:
SHIN J-S; KIM K-S; KIM M-B; JEONG J-H; KIM B-K: "Synthesis and hypoglycemic effect of chrysin derivatives", BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 9, no. 6, 22 March 1999 (1999-03-22), pages 869 - 874, XP004160490, ISSN: 0960-894X, DOI: 10.1016/S0960-894X(99)00092-X
TSUTOMU SHIMADA; TAKUMI HORIKAWA; YUKINOBU IKEYA; HIROTAKA MATSUO; KAORU KINOSHITA; TAKAAKI TAGUCHI; KOJI ICHINOSE; KUNIO TAKAHASH: "Preventive effect of Kaempferia parviflora ethyl acetate extract and its major components polymethoxyflavonoid on metabolic diseases", FITOTERAPIA, vol. 82, no. 8, 31 December 2011 (2011-12-31), pages 1272 - 1278, XP028322593, ISSN: 0367-326X, DOI: :10.1016/j.fitote.2011.08.018
See also references of EP 3747435A4
TSUTOMU SHIMADA; TAKUMI HORIKAWA; YUKINOBU IKEYA; HIROTAKA MATSUO; KAORU KINOSHITA; TAKAAKI TAGUCHI; KOJI ICHINOSE; KUNIO TAKAHASH: "Preventive effect of Kaempferia parviflora ethyl acetate extract and its major components polymethoxyflavonoid on metabolic diseases", FITOTERAPIA, vol. 82, no. 8, 31 December 2011 (2011-12-31), pages 1272 - 1278, XP028322593, ISSN: 0367-326X, DOI: :10.1016/j.fitote.2011.08.018
See also references of EP 3747435A4
Attorney, Agent or Firm:
LEE, Jeong-Hoon (KR)
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