Title:
PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING EPIDEMIC RNA VIRAL INFECTIOUS DISEASE
Document Type and Number:
WIPO Patent Application WO/2021/194290
Kind Code:
A1
Abstract:
The present invention relates to a use of pyronaridine or a pharmaceutically acceptable salt thereof, and/or artemisinin or a derivative thereof for preventing or treating an epidemic RNA viral infectious disease, and more specifically, to a pharmaceutical composition for preventing or treating an epidemic RNA viral infectious disease, in particular, Coronavirus Disease 2019 (COVID-19), the composition comprising a therapeutically effective amount of pyronaridine or a pharmaceutically acceptable salt thereof, and/or artemisinin or a derivative thereof, together with a pharmaceutically acceptable carrier.
More Like This:
Inventors:
RYU JEI MAN (KR)
JU CHUNG (KR)
CHUNG HYUN KYU (KR)
CHO GEUM SIL (KR)
JU CHUNG (KR)
CHUNG HYUN KYU (KR)
CHO GEUM SIL (KR)
Application Number:
PCT/KR2021/003742
Publication Date:
September 30, 2021
Filing Date:
March 25, 2021
Export Citation:
Assignee:
SHIN POONG PHARMACEUTICAL CO LTD (KR)
International Classes:
A61K31/167; A61K31/4738; A61K31/37; A61K31/7056; A61K38/21; A61K45/06; A61P31/14
Foreign References:
| US20070142459A1 | 2007-06-21 | |||
| KR20060039286A | 2006-05-08 | |||
| US20150196530A1 | 2015-07-16 |
Other References:
LANE THOMAS R., MASSEY CHRISTOPHER, COMER JASON E., ANANTPADMA MANU, FREUNDLICH JOEL S., DAVEY ROBERT A., MADRID PETER B., EKINS S: "Repurposing the antimalarial pyronaridine tetraphosphate to protect against Ebola virus infection", PLOS NEGLECTED TROPICAL DISEASES, vol. 13, no. 11, 21 November 2019 (2019-11-21), pages 1 - 26, XP055853399, ISSN: 1935-2735, DOI: 10.1371/journal.pntd.0007890
PRYCE JOSEPH, HINE PAUL: "Pyronaridine-artesunate for treating uncomplicated Plasmodium falciparum malaria", COCHRANE DATABASE OF SYSTEMATIC REVIEWS, 8 January 2019 (2019-01-08), pages 1 - 98, XP055853401, DOI: 10.1002/14651858.CD006404.pub3
PETERS W., ROBINSON B. L.: "The chemotherapy of rodent malaria. LV. Interactions between pyronaridine and artemisinin", ANNALS OF TROPICAL MEDICINE & PARASITOLOGY, vol. 91, no. 2, 1 March 1997 (1997-03-01), pages 141 - 145, XP009530984, ISSN: 0003-4983, DOI: 10.1080/00034983.1997.11813123
JOON-YONG BAE, GEE EUN LEE, HEEDO PARK, JUYOUNG CHO, YUNG-EUI KIM, JOO-YEON LEE, CHUNG JU, WON-KI KIM, JIN IL KIM, MAN-SEONG PARK: "Pyronaridine and artesunate are potential antiviral drugs against COVID-19 and influenza", BIORXIV, 28 July 2020 (2020-07-28), pages 1 - 10, XP055853402, DOI: 10.1101/2020.07.28.225102
KRISHNA SANJEEV; AUGUSTIN YOLANDA; WANG JIGANG; XU CHENGCHAO; STAINES HENRY M.; PLATTEEUW HANS; KAMARULZAMAN ADEEBA; SALL AMADOU; : "Repurposing Antimalarials to Tackle the COVID-19 Pandemic", TRENDS IN PARASITOLOGY, vol. 37, no. 1, 19 October 2020 (2020-10-19), GB, pages 8 - 11, XP086412305, ISSN: 1471-4922, DOI: 10.1016/j.pt.2020.10.003
"Remington's Pharmaceutical Science", 1975, MACK PUBLISHING COMPANY
"Remington's Pharmaceutical Sciences", 1995, MACK PUBLISHING COMPANY
PRYCE JOSEPH, HINE PAUL: "Pyronaridine-artesunate for treating uncomplicated Plasmodium falciparum malaria", COCHRANE DATABASE OF SYSTEMATIC REVIEWS, 8 January 2019 (2019-01-08), pages 1 - 98, XP055853401, DOI: 10.1002/14651858.CD006404.pub3
PETERS W., ROBINSON B. L.: "The chemotherapy of rodent malaria. LV. Interactions between pyronaridine and artemisinin", ANNALS OF TROPICAL MEDICINE & PARASITOLOGY, vol. 91, no. 2, 1 March 1997 (1997-03-01), pages 141 - 145, XP009530984, ISSN: 0003-4983, DOI: 10.1080/00034983.1997.11813123
JOON-YONG BAE, GEE EUN LEE, HEEDO PARK, JUYOUNG CHO, YUNG-EUI KIM, JOO-YEON LEE, CHUNG JU, WON-KI KIM, JIN IL KIM, MAN-SEONG PARK: "Pyronaridine and artesunate are potential antiviral drugs against COVID-19 and influenza", BIORXIV, 28 July 2020 (2020-07-28), pages 1 - 10, XP055853402, DOI: 10.1101/2020.07.28.225102
KRISHNA SANJEEV; AUGUSTIN YOLANDA; WANG JIGANG; XU CHENGCHAO; STAINES HENRY M.; PLATTEEUW HANS; KAMARULZAMAN ADEEBA; SALL AMADOU; : "Repurposing Antimalarials to Tackle the COVID-19 Pandemic", TRENDS IN PARASITOLOGY, vol. 37, no. 1, 19 October 2020 (2020-10-19), GB, pages 8 - 11, XP086412305, ISSN: 1471-4922, DOI: 10.1016/j.pt.2020.10.003
"Remington's Pharmaceutical Science", 1975, MACK PUBLISHING COMPANY
"Remington's Pharmaceutical Sciences", 1995, MACK PUBLISHING COMPANY
Attorney, Agent or Firm:
HANSUNG INTELLECTUAL PROPERTY (KR)
Download PDF: