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Patent Searching and Data


Title:
PHARMACEUTICAL COMPOSITION, FOR PREVENTING OR TREATING HEPATIC FIBROSIS, COMPRISING 8-OHDG
Document Type and Number:
WIPO Patent Application WO/2017/209466
Kind Code:
A1
Abstract:
The present invention relates to: a pharmaceutical composition, for preventing or treating hepatic fibrosis or cirrhosis, comprising 8-OHdG or pharmaceutically acceptable salts of same; a method for preventing or treating hepatic fibrosis or cirrhosis by means of the pharmaceutical composition; and a food composition, for remedying hepatic fibrosis or cirrhosis, comprising 8-OHdG or pharmaceutically acceptable salts of same. By means of the pharmaceutical composition for preventing or treating hepatic fibrosis or cirrhosis of the present invention, the level of various markers having increased expression levels due to induced hepatic fibrosis can be decreased and thus the pharmaceutical composition can widely be utilized for effective prevention or treatment of hepatic fibrosis or cirrhosis induced by the hepatic fibrosis.

Inventors:
SHIN, Seung Kak (110-508, 15 Gwangpyeong-ro 10-gil,,Gangnam-gu, Seoul, 06360, KR)
KWON, Oh Sang (733-1502, 119 Gwangjeong-ro,,Gunpo-si, Gyeonggi-do, 15825, KR)
CHUNG, Myung Hee (21 Namdong-daero 774beon-gil, Namdong-gu, Incheon, 21565, KR)
Application Number:
KR2017/005574
Publication Date:
December 07, 2017
Filing Date:
May 29, 2017
Export Citation:
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Assignee:
GIL MEDICAL CENTER (21 Namdong-daero 774beon-gil, Namdong-gu, Incheon, 21565, KR)
International Classes:
A61K31/708; A23L33/10
Foreign References:
KR20100085697A2010-07-29
KR101135574B12012-04-23
KR101086040B12011-11-22
Other References:
ICHIBA, M. ET AL.: "Expression of 8-hydroxy-2'-Deoxyguanosine in Chronic Liver Disease and Hepatocellular Carcinoma", LIVER INTERNATIONAL, vol. 23, 2003, pages 338 - 345, XP055445963
OCK, C.-Y. ET AL.: "8-Hydroxydeoxyguanosine: Not Mere Biomarker for Oxidative Stress, but Remedy for Oxidative Stress-implicated Gastrointestinal Diseases", WORLD JOURNAL OF GASTROENTEROLOGY, vol. 18, no. 4, 2012, pages 302 - 308, XP055445964
Attorney, Agent or Firm:
SON, Min (Hanol Intellectual Property&Law, 6th Floor 163, YangJaeCheon-ro,,Gangnam-gu, Seoul, 06302, KR)
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