PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING MUSCULAR WEAKNESS-RELATED DISEASES, CONTAINING BUTYLPYRIDINIUM OR DERIVATIVE THEREOF

WIPO Patent Application WO/2015/190643

A1

The present invention relates to a composition for promoting the differentiation of myoblasts, the composition containing butylpyridinium, a derivative thereof, or a pharmaceutically acceptable salt thereof; a pharmaceutical composition for preventing or treating muscular weakness-related diseases; a food composition for preventing or alleviating muscular weakness-related diseases; a composition for strengthening muscular strength; and a feed or feed composition for strengthening muscular strength. Furthermore, the present invention relates to a method for promoting the differentiation of myoblasts using butylpyridinium, a derivative thereof, or a pharmaceutically acceptable salt thereof; a method for manufacturing differentiated myoblasts; and a method for treating muscular weakness-related diseases.

KWON KI SUN (KR)
PARK SUNG SUP (KR)
CHUNG SUN GUN (KR)
LEE KWANG PYO (KR)
LEE SEUNG MIN (KR)
CHOI JUNG YI (KR)

PCT/KR2014/006416

December 17, 2015

July 16, 2014

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KOREA RES INST OF BIOSCIENCE (KR)
SNU R&DB FOUNDATION (KR)

A61K31/4425; A61K31/435; A61P21/00

WO2013177176A1

2013-11-28

JP2006517565A	2006-07-27
KR20140042759A	2014-04-07
KR20130117017A	2013-10-25

OSSES, NELSON ET AL.: "Inhibition of extracellular matrix assembly induces the expression of osteogenic markers in skeletal muscle cells by a BMP-2 independent mechanism", BMC CELL BIOLOGY, vol. 10, no. 73, 2009, pages 1 - 17, XP021062018
See also references of EP 3156055A4

SON, MIN (KR)
손민 (KR)

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