Title:
PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING RESPIRATORY DISEASE COMPRISING EXTRACT OF JUSTICIA PROCUMBENS L.
Document Type and Number:
WIPO Patent Application WO/2017/179931
Kind Code:
A1
Abstract:
The present invention relates to a pharmaceutical composition for preventing or treating respiratory diseases which comprises an alcohol or organic solvent extract of Justicia procumbens L. as an active ingredient, and a pharmaceutical composition for preventing or treating respiratory diseases which comprises an alcohol or organic solvent extract of Justicia procumbens L. comprising any one of Justicidin A, Justicidin B, Justicidin C and Phyllamyricin C, and a food composition thereof for preventing or ameliorating respiratory diseases. The composition comprising an extract of Justicia procumbens L. of the present invention can inhibit the abnormal hyperplasia of spleen cells, inhibit the secretion of allergic inflammatory cytokines, and exhibit a sputum-releasing effect and an airway contraction-inhibiting effect, and thus can effectively prevent, treat or ameliorate respiratory diseases.
Inventors:
YOON JOO BYOUNG (KR)
LEE HYUN YONG (KR)
YOUM JI HYUN (KR)
KIM KWANG-HYUN (KR)
JEON JI HYUN (KR)
CHANG HWAN BONG (KR)
WOO JI YOUNG (KR)
YOON MI HEE (KR)
CHOI MIN SOO (KR)
CHOI DONG RACK (KR)
LEE HYUN YONG (KR)
YOUM JI HYUN (KR)
KIM KWANG-HYUN (KR)
JEON JI HYUN (KR)
CHANG HWAN BONG (KR)
WOO JI YOUNG (KR)
YOON MI HEE (KR)
CHOI MIN SOO (KR)
CHOI DONG RACK (KR)
Application Number:
PCT/KR2017/004033
Publication Date:
October 19, 2017
Filing Date:
April 13, 2017
Export Citation:
Assignee:
DONG WHA PHARM CO LTD (KR)
International Classes:
A61K36/19; A23L33/10; A23L33/105; A61K31/343; A61K31/36
Foreign References:
| JP2007230977A | 2007-09-13 | |||
| KR20160044807A | 2016-04-26 |
Other References:
CORREA, G. M. ET AL.: "Chemical Constituents and Biological Activities of Species of Justicia-a Review", REVISTA BRASILEIRA DE FARMACOGNOSIA BRAZILIAN JOURNAL OF PHARMACOGNOSY, vol. 22, no. 1, 2012, pages 220 - 238, XP055269583
DOGRA, K. S. ET AL.: "Assessment of Indian Medicinal Plants for the Treatment of Asthma", JOURNAL OF MEDICINAL PLANTS RESEARCH, vol. 9, no. 32, 2015, pages 851 - 862, XP055430600
ZHOU, P. ET AL.: "Preparative Isolation and Purification of Lignans from Justicia Procumberis Using High-speed Counter-current Chromatography in Stepwise Elution Mode", MOLECULES, vol. 20, 2015, pages 7048 - 7058, XP055430602
VELPANDIAN, V. ET AL.: "Clinical Evaluation of Justicia Tranquebariensis L. in the Management of Bronchial Asthma", AMERICAN JOURNAL OF PHYTOMEDICINE AND CLINICAL THERAPEUTICS, vol. 9, no. 2, 2014, pages 1103 - 1111, XP055430606
See also references of EP 3443972A4
DOGRA, K. S. ET AL.: "Assessment of Indian Medicinal Plants for the Treatment of Asthma", JOURNAL OF MEDICINAL PLANTS RESEARCH, vol. 9, no. 32, 2015, pages 851 - 862, XP055430600
ZHOU, P. ET AL.: "Preparative Isolation and Purification of Lignans from Justicia Procumberis Using High-speed Counter-current Chromatography in Stepwise Elution Mode", MOLECULES, vol. 20, 2015, pages 7048 - 7058, XP055430602
VELPANDIAN, V. ET AL.: "Clinical Evaluation of Justicia Tranquebariensis L. in the Management of Bronchial Asthma", AMERICAN JOURNAL OF PHYTOMEDICINE AND CLINICAL THERAPEUTICS, vol. 9, no. 2, 2014, pages 1103 - 1111, XP055430606
See also references of EP 3443972A4
Attorney, Agent or Firm:
AHN, So Young (KR)
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