Title:
PHARMACEUTICAL COMPOSITION FOR PREVENTION OR TREATMENT OF ALLERGIC DISEASES, CONTAINING DEAD CELLS OF STREPTOCOCCUS PYOGENES OR SPEA PROTEIN
Document Type and Number:
WIPO Patent Application WO/2024/071736
Kind Code:
A1
Abstract:
An aspect of the present invention relates to a pharmaceutical composition for the prevention or treatment of allergic diseases, containing dead cells of Streptococcus pyogenes or Streptococcal pyrogenic Exotoxin A (SpeA) protein. The dead cells of Streptococcus Pyogenes or SpeA protein according to an aspect exhibits the excellent effect in patients with allergic diseases of increasing body temperature, palliating symptoms of dermatitis and itching, reducing the thickness of epithelial tissues, and lowering the expression levels of IgE, IFN-γ, and IL-4 proteins in serum , and thus can be advantageously utilized for the prevention, alleviation, or treatment of allergic diseases.
Inventors:
KIM JEONG JIN (KR)
Application Number:
PCT/KR2023/013583
Publication Date:
April 04, 2024
Filing Date:
September 11, 2023
Export Citation:
Assignee:
COMBIMED CO LTD (KR)
International Classes:
A61K35/744; A23L33/135; A23L33/195; A61K8/64; A61K8/99; A61K38/16; A61P37/08; A61Q19/00; C12N1/20
Foreign References:
| KR20150146461A | 2015-12-31 | |||
| KR20120047792A | 2012-05-14 | |||
| US20130045291A1 | 2013-02-21 | |||
| US4929547A | 1990-05-29 | |||
| KR102507470B1 | 2023-03-10 |
Attorney, Agent or Firm:
ISIS IP LAW LLC (KR)
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