Title:
PHARMACEUTICAL COMPOSITION FOR PREVENTION OR TREATMENT OF FIBROSIS CONTAINING PLATYCODI
RADIX EXTRACT AS EFFECTIVE INGREDIENT
Document Type and Number:
WIPO Patent Application WO/2019/009525
Kind Code:
A1
Abstract:
The preset invention relates to a pharmaceutical composition for prevention or treatment of steatofibrosis containing a platycodi
radix extract as an effective ingredient. The platycodi
radix extract according to the present invention has excellent effects of inhibiting accumulation of connective tissue in adipose tissue and inhibiting infiltration of macrophages such that the extract can be effectively used for the prevention or treatment of steatofibrosis.
Inventors:
CHOI MYUNG-SOOK (KR)
KIM YE JIN (KR)
KWON EUN-YOUNG (KR)
RYU RI (KR)
KIM YE JIN (KR)
KWON EUN-YOUNG (KR)
RYU RI (KR)
Application Number:
PCT/KR2018/006418
Publication Date:
January 10, 2019
Filing Date:
June 05, 2018
Export Citation:
Assignee:
KYUNGPOOK NAT UNIV IND ACADEMIC COOP FOUND (KR)
International Classes:
A61K36/346; A23L33/105
Domestic Patent References:
| WO2016153262A2 | 2016-09-29 |
Foreign References:
| KR20040028020A | 2004-04-03 | |||
| KR20160101535A | 2016-08-25 | |||
| CN104306896A | 2015-01-28 |
Other References:
LIM, J-H ET AL.: "Protective Effect of the Roots Extract of Platycodon Grandiflorum on Bile Duct Ligation-induced Hepatic Fibrosis in Rats", HUMAN & EXPERIMENTAL TOXICOLOGY, vol. 32, no. 11, 19 February 2013 (2013-02-19), pages 1197 - 1205, XP008169573
LEE , KYUNG JIN ET AL.: "Suppressive Effects of Platycodon Grandiflorum on the Progress of Carbon Tetrachlonde-Induced Hepatic Fibrosis", ARCHIVES OF PHARMACAL RESEARCH, vol. 27, no. 12, December 2004 (2004-12-01), pages 1238 - 1244, XP053007037
LEE , KYUNG JIN ET AL.: "Suppressive Effects of Platycodon Grandiflorum on the Progress of Carbon Tetrachlonde-Induced Hepatic Fibrosis", ARCHIVES OF PHARMACAL RESEARCH, vol. 27, no. 12, December 2004 (2004-12-01), pages 1238 - 1244, XP053007037
Attorney, Agent or Firm:
LEE, Myoung-Jin (KR)
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