Title:
PHARMACEUTICAL COMPOSITION FOR PREVENTION OR TREATMENT OF FIBROSIS
Document Type and Number:
WIPO Patent Application WO/2022/240036
Kind Code:
A1
Abstract:
The present invention relates to a pharmaceutical composition that can be usefully used for the prevention or treatment of fibrosis. By using a first component and a second component together according to the present invention, the prevention or treatment effect on fibrosis can be further enhanced.
Inventors:
BAE DA JEONG (KR)
LEE CAROLINE HEE (KR)
CHO MIN JAE (KR)
PARK MIN YOUNG (KR)
KIM JI HYEON (KR)
PARK JOON SEOK (KR)
LEE CAROLINE HEE (KR)
CHO MIN JAE (KR)
PARK MIN YOUNG (KR)
KIM JI HYEON (KR)
PARK JOON SEOK (KR)
Application Number:
PCT/KR2022/006231
Publication Date:
November 17, 2022
Filing Date:
May 02, 2022
Export Citation:
Assignee:
DAEWOONG PHARMACEUTICAL CO LTD (KR)
International Classes:
A61K31/454; A61K31/4418; A61K31/496; A61P11/00; A61P43/00
Domestic Patent References:
| WO2010018134A1 | 2010-02-18 |
Foreign References:
| US20190282565A1 | 2019-09-19 | |||
| KR102084772B1 | 2020-03-04 | |||
| KR102084772B1 | 2020-03-04 |
Other References:
LEE C.H., CHO M., KIM J.M., LEE J.H., KIM D.-W., PARK M.Y., KIM Y.K., HAN J., PARK J.S.: "A First-in-Class PRS Inhibitor, DWN12088, as a novel therapeutic agent for idiopathic pulmonary fibrosis", AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, vol. 201, 1 January 2020 (2020-01-01), US , pages A2786, XP009541055, ISSN: 1073-449X
SONG DAE-GEUN, KIM DOYEUN, JUNG JAE WOO, NAM SEO HEE, KIM JI EON, KIM HYE-JIN, KIM JONG HYUN, PAN CHEOL-HO, KIM SUNGHOON, LEE JUNG: "Glutamyl-Prolyl-tRNA Synthetase Regulates Epithelial Expression of Mesenchymal Markers and Extracellular Matrix Proteins: Implications for Idiopathic Pulmonary Fibrosis", FRONTIERS IN PHARMACOLOGY, vol. 9, no. 1337, pages 1 - 11, XP093004347, DOI: 10.3389/fphar.2018.01337
NATURE, vol. 494, 2013, pages 121 - 125
NAT. REV. CANCER, vol. 11, 2011, pages 708 - 718
SONG DAE-GEUN, KIM DOYEUN, JUNG JAE WOO, NAM SEO HEE, KIM JI EON, KIM HYE-JIN, KIM JONG HYUN, PAN CHEOL-HO, KIM SUNGHOON, LEE JUNG: "Glutamyl-Prolyl-tRNA Synthetase Regulates Epithelial Expression of Mesenchymal Markers and Extracellular Matrix Proteins: Implications for Idiopathic Pulmonary Fibrosis", FRONTIERS IN PHARMACOLOGY, vol. 9, no. 1337, pages 1 - 11, XP093004347, DOI: 10.3389/fphar.2018.01337
NATURE, vol. 494, 2013, pages 121 - 125
NAT. REV. CANCER, vol. 11, 2011, pages 708 - 718
Attorney, Agent or Firm:
YOU ME PATENT AND LAW FIRM (KR)
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