PHARMACEUTICAL COMPOSITION FOR PREVENTION AND TREATMENT OF MENOPAUSAL SYMPTOMS, CONTAINING, AS ACTIVE INGREDIENT, MIXTURE OF CURCUMA LONGA AND LICORICE EXTRACTS

WIPO Patent Application WO/2017/069506

A1

The present invention relates to a pharmaceutical composition for the prevention and treatment of menopausal symptoms, which contains, as an active ingredient, a mixture of Curcuma longa and licorice extracts. Specifically, the licorice may be heat-roasted licorice, but is not limited thereto, and the mixture of Curcuma longa and licorice extracts increases estrogen activity in human breast cancer cells (MCF-7), inhibits lipid accumulation in human liver cancer cells (HepG-2), and has effects of inhibiting lipid accumulation, suppressing weight gain, and improving liver protective activity and blood lipid concentration in animal models with menopausal hyperlipidemia induced through a high-fat and high-cholesterol diet after ovariectomy, and therefore, the mixture of Curcuma longa and licorice extracts of the present invention can be advantageously used as a pharmaceutical composition for the prevention and treatment of menopausal symptoms.

KO KYUNG-NAM (KR)
KO BYOUNG SEOB (KR)
PARK IN SIL (KR)
RYUK JIN AH (KR)
GO HIROE (KR)
LEE HYE WON (KR)

PCT/KR2016/011736

April 27, 2017

October 19, 2016

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AGRICULTURAL CORP JEJUHAWANGULGUM CO LTD (KR)
KOREA INST ORIENTAL MEDICINE (KR)

A61K36/9066; A23L33/105; A61K36/484

JP2003113117A	2003-04-18
KR100360674B1	2002-11-13
KR101515915B1	2015-04-29
JP2006325457A	2006-12-07

WIDECOVERAGE ONLINE NEWS TEAM: "Danggijakyaksan, Being Effective for Improvement of Blood Circulation During Menopause", 16 April 2015 (2015-04-16), Retrieved from the Internet

SON, Min (KR)

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