PHARMACEUTICAL COMPOSITION FOR SUPPRESSING ORGAN FIBROSIS

Title:

PHARMACEUTICAL COMPOSITION FOR SUPPRESSING ORGAN FIBROSIS

Document Type and Number:

WIPO Patent Application WO/2023/140350

Kind Code:

A1

Abstract:

The present invention provides a pharmaceutical composition for suppressing organ fibrosis, characterized by having an angiotensin II receptor antagonist as an active ingredient, and being administered at a dosage of 0.2 times or less the dosage as an antihypertensive drug per day.

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Inventors:

LI TAO-SHENG (JP)
GU WEILI (JP)

Application Number:

PCT/JP2023/001676

Publication Date:

July 27, 2023

Filing Date:

January 20, 2023

Export Citation:

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Assignee:

UNIV NAGASAKI (JP)

International Classes:

A61K45/00; A61K31/4178; A61P1/16; A61P13/12; A61P29/00; A61P43/00

Domestic Patent References:

WO2017170434A1	2017-10-05
WO2021130038A1	2021-07-01

Foreign References:

JP2019519595A	2019-07-11
JP2010511712A	2010-04-15
JP2018507244A	2018-03-15

Other References:

YOSHIJI HITOSHI; NOGUCHI RYUICHI; IKENAKA YASUHIDE; NAMISAKI TADASHI; KITADE MITSUTERU; KAJI KOSUKE; SHIRAI YUSAKU; YOSHII JUNICHI: "Losartan, an angiotensin-II type 1 receptor blocker, attenuates the liver fibrosis development of non-alcoholic steatohepatitis in the rat", BMC RESEARCH NOTES, BIOMED CENTRAL LTD, GB, vol. 2, no. 1, 5 May 2009 (2009-05-05), GB , pages 70, XP021052834, ISSN: 1756-0500, DOI: 10.1186/1756-0500-2-70

Attorney, Agent or Firm:

IWATANI Ryo (JP)

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