PHARMACEUTICAL COMPOSITION FOR TREATING CANCER, CONTAINING LACTATE METAL SALT

Title:

PHARMACEUTICAL COMPOSITION FOR TREATING CANCER, CONTAINING LACTATE METAL SALT

Document Type and Number:

WIPO Patent Application WO/2016/108446

Kind Code:

A1

Abstract:

The present invention relates to: a pharmaceutical composition for treating cancer containing, as an active ingredient, a lactate metal salt, which can be dissociated, in cancer cells, into lactate capable of effectively inhibiting actions such as proliferation, invasion, and metastasis of cancer cells by disturbing the metabolic processes of cancer cells; a pharmaceutical composition for inhibiting cancer metastasis; a food composition for alleviating cancer; and a method for treating cancer and a method for inhibiting cancer metastasis, both methods comprising a step of administering the lactate metal salt. The lactate metal salt of the present invention inhibits the growth of cancer cells and induces the death of cancer cells by disturbing the metabolic processes in the main energy production pathways of cancer, and inhibits the expression of factors inducing resistance against radiation exposure, while having no side effects. Therefore, the lactate metal salt can be widely utilized in a more effective anti-cancer therapy.

Inventors:

KIM HWAN MOOK (KR)
JEONG KEUN YEONG (KR)
SIM JAE JUN (KR)
JANG YEONG SU (KR)

Application Number:

PCT/KR2015/013191

Publication Date:

July 07, 2016

Filing Date:

December 04, 2015

Export Citation:

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Assignee:

UNIV GACHON IND ACAD COOP FOUND (KR)

International Classes:

A61K31/19; A23L33/10; A61K9/00; A61K9/08; A61K9/48; A61K9/70; A61K31/191; A61K31/506; A61K45/06

Domestic Patent References:

WO2010111650A2	2010-09-30
WO2003063836A1	2003-08-07

Foreign References:

US20110117210A1	2011-05-19
US6306902B1	2001-10-23
EP2799060A1	2014-11-05

Other References: