Title:
PHARMACEUTICAL COMPOSITION FOR TREATING COLORECTAL DISEASE CONTAINING CYSTATIN AND A PROTEIN DERIVED FROM LACTIC ACID BACTERIA
Document Type and Number:
WIPO Patent Application WO/2018/139703
Kind Code:
A1
Abstract:
The present invention relates to a pharmaceutical composition for treating colorectal disease, which contains cystatin and a protein derived from lactic acid bacteria. The pharmaceutical composition of the present invention, which contains cystatin and the protein derived from lactic acid bacteria, exhibits a significantly increased inhibitory effect against colorectal cancer compared to when cystatin and the protein derived from lactic acid bacteria are used alone. Thus, the pharmaceutical composition of the present invention will be effectively used as a therapeutic agent against colorectal cancer in the medical field.
Inventors:
CHUNG MYUNG JUN (KR)
Application Number:
PCT/KR2017/002512
Publication Date:
August 02, 2018
Filing Date:
March 08, 2017
Export Citation:
Assignee:
CELL BIOTECH CO LTD (KR)
International Classes:
A61K38/16; A23L33/135; A23L33/18; A61K35/744; A61K35/747; A61K38/00
Domestic Patent References:
| WO2013077534A1 | 2013-05-30 |
Foreign References:
| US20140038902A1 | 2014-02-06 |
Other References:
VALLE N. ET AL.: "Cystatin D is a candidate tumor suppressor gene induced by vitamin D in human colon cancer cells", THE JOURNAL OF CLINICAL INVESTIGATION, vol. 119, no. 8, 3 August 2009 (2009-08-03), pages 2343 - 2358, XP055531718
SADEGHI-ALIABADI ET AL.: "Effects of Lactobacillus plantarum A7 with probiotic potential on colon cancer and normal cells proliferation in comparison with a commercial strain", IRANIAN JOURNAL OF BASIC MEDICAL SCIENCES, vol. 17, no. 10, October 2014 (2014-10-01), pages 815 - 819, XP055531730
ZHONG ET AL.: "Emerging roles of lactic acid bacteria in protection against colorectal cancer", WORLD JOURNAL OF GASTROENTEROLOGY, vol. 20, no. 24, 2014, pages 7878 - 7886, XP055531727
SADEGHI-ALIABADI ET AL.: "Effects of Lactobacillus plantarum A7 with probiotic potential on colon cancer and normal cells proliferation in comparison with a commercial strain", IRANIAN JOURNAL OF BASIC MEDICAL SCIENCES, vol. 17, no. 10, October 2014 (2014-10-01), pages 815 - 819, XP055531730
ZHONG ET AL.: "Emerging roles of lactic acid bacteria in protection against colorectal cancer", WORLD JOURNAL OF GASTROENTEROLOGY, vol. 20, no. 24, 2014, pages 7878 - 7886, XP055531727
Attorney, Agent or Firm:
HONESTY & JR PARTNERS INTELLECTUAL PROPERTY LAW GROUP (KR)
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