PHARMACEUTICAL COMPOSITION FOR TREATING COLORECTAL DISEASE CONTAINING CYSTATIN A

WIPO Patent Application WO/2018/164295

A1

The present invention relates to a pharmaceutical composition for treating colorectal disease, which contains cystatin A. The pharmaceutical composition of the present invention, which contains cystatin A, exhibits a significantly increased inhibitory effect against colorectal cancer compared to when cystatin is not used. Thus, the pharmaceutical composition of the present invention will be effectively used as a therapeutic agent against colorectal cancer in the medical field.

CHUNG MYUNG JUN (KR)

PCT/KR2017/002514

September 13, 2018

March 08, 2017

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CELL BIOTECH CO LTD (KR)

A61K38/00; A23L33/18

WO2008054635A2

2008-05-08

US20080019910A1

2008-01-24

LI ET AL.: "Overexpression of stefin A in human esophageal squamous cell carcinoma cells inhibits tumor cell growth, angiogenesis, invasion, and metastasis", CLINICAL CANCER RESEARCH, vol. 11, no. 24, 2015, pages 8753 - 8762, XP055549472
BIAN ET AL.: "Cathepsin B promotes colorectal tumorigenesis, cell invasion, and metastasis", MOLECULAR CARCINOGENESIS, vol. 55, no. 5, 2016, pages 671 - 687, XP055549480
KOS ET AL.: "Cysteine proteinase inhibitors stefin A, stefin B, and cystatin C in sera from patients with colorectal cancer: relation to prognosis", CLINICAL CANCER RESEARCH, vol. 6, 2000, pages 505 - 511, XP055549488

HONESTY & JR PARTNERS INTELLECTUAL PROPERTY LAW GROUP (KR)

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