Title:
PHARMACEUTICAL COMPOSITION FOR TREATING DIABETES, COMPRISING PANCREATIC ISLET CELLS AND ELASTIN-LIKE ARTIFICIAL EXTRACELLULAR MATRIX
Document Type and Number:
WIPO Patent Application WO/2017/078439
Kind Code:
A1
Abstract:
The present invention relates to a pharmaceutical composition for treating diabetes comprising pancreatic islet cells and an elastin-like artificial extracellular matrix (REP) and, more specifically, to a pharmaceutical composition for treating diabetes which can treat diabetes more effectively by increasing the survival rate of transplanted pancreatic islet cells and rapidly restoring normal blood sugar levels and maintaining same for a long time, by reacting pancreatic islet cells with an elastin-like artificial extracellular matrix and then administering same along with the elastin-like artificial extracellular matrix.
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Inventors:
LEE KYEONG MIN (KR)
JEON WON BAE (KR)
KIM JUNG HEE (KR)
JEON WON BAE (KR)
KIM JUNG HEE (KR)
Application Number:
PCT/KR2016/012611
Publication Date:
May 11, 2017
Filing Date:
November 03, 2016
Export Citation:
Assignee:
DAEGU GYEONGBUK INST SCIENCE & TECH (KR)
International Classes:
A61K35/39; A61K38/39
Foreign References:
| KR101429346B1 | 2014-08-12 | |||
| KR101350900B1 | 2014-01-14 | |||
| KR20140103985A | 2014-08-27 |
Other References:
LEE, K. -M. ET AL.: "Effects of Arg-Gly-Asp-modified Elastin-like Polypeptide on Pseudoislet Fonnation via Up-regulation of Cell Adhesion Molecules and Exuacelluiar Matrix Proteins", ACTA BIOMATERIALIA, vol. 9, no. 3, 2013, pages 5600 - 5608, XP055382051
KIM, M. J. ET AL.: "Pancreas-like Extracellular Matrix Scaffold for Successful Pancreatic Islet Transplantation", MACROMOLECULAR RESEARCH, vol. 22, no. 6, 2014, pages 575 - 582, XP055382052
KIM, M. J. ET AL.: "Pancreas-like Extracellular Matrix Scaffold for Successful Pancreatic Islet Transplantation", MACROMOLECULAR RESEARCH, vol. 22, no. 6, 2014, pages 575 - 582, XP055382052
Attorney, Agent or Firm:
ERUUM & LEEON INTELLECTUAL PROPERTY LAW FIRM (KR)
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