Title:
PHARMACEUTICAL COMPOSITION FOR TREATING DIABETES
Document Type and Number:
WIPO Patent Application WO/2013/065835
Kind Code:
A1
Abstract:
A compound represented by general formula (I) or a pharmaceutically acceptable salt thereof. This novel compound has an ability of activating a glycogen synthase, but rarely activates a receptor, i.e., a PPAR, and is highly safe. (In the formula, Ar represents an aromatic carbon ring or a heterocyclic ring; and Ar2 represents any one of the below-mentioned rings or the like.)
Inventors:
NAKAGAWA TADAKIYO (JP)
MATSUMOTO KAYO (JP)
TAKESHITA SEN (JP)
YOSHIDA TOMOMI (JP)
TOKUMASU MUNETAKA (JP)
INOUE HIROKI (JP)
KOBAYASHI KAORI (JP)
MATSUMOTO KAYO (JP)
TAKESHITA SEN (JP)
YOSHIDA TOMOMI (JP)
TOKUMASU MUNETAKA (JP)
INOUE HIROKI (JP)
KOBAYASHI KAORI (JP)
Application Number:
PCT/JP2012/078516
Publication Date:
May 10, 2013
Filing Date:
November 02, 2012
Export Citation:
Assignee:
AJINOMOTO KK (JP)
International Classes:
C07D207/16; A61K31/343; A61K31/397; A61K31/401; A61K31/4025; A61K31/404; A61K31/427; A61K31/536; A61P3/10; A61P43/00; C07D307/79; C07D403/12; C07D405/12; C07D409/12; C07D413/12
Domestic Patent References:
| WO2011058154A1 | 2011-05-19 | |||
| WO2005000781A1 | 2005-01-06 | |||
| WO2006058648A2 | 2006-06-08 | |||
| WO2011057956A1 | 2011-05-19 | |||
| WO2011057959A1 | 2011-05-19 | |||
| WO2011057993A1 | 2011-05-19 | |||
| WO2011058122A1 | 2011-05-19 | |||
| WO2011058154A1 | 2011-05-19 | |||
| WO2011067174A1 | 2011-06-09 | |||
| WO2011067266A1 | 2011-06-09 |
Foreign References:
| JP2007506666A | 2007-03-22 | |||
| JP2008521846A | 2008-06-26 |
Other References:
See also references of EP 2774917A4
JOURNAL OF CLINICAL AND EXPERIMENTAL MEDICINE, vol. 220, no. 1, 2007, pages 75 - 80
THE JOUNAL OF BIOLOGICAL CHEMISTRY, vol. 274, no. 51, 1999, pages 36293 - 36299
THE JOUNAL OF BIOLOGICAL CHEMISTRY, vol. 270, no. 22, 1995, pages 12953 - 12956
JOURNAL OF CLINICAL AND EXPERIMENTAL MEDICINE, vol. 220, no. 1, 2007, pages 75 - 80
THE JOUNAL OF BIOLOGICAL CHEMISTRY, vol. 274, no. 51, 1999, pages 36293 - 36299
THE JOUNAL OF BIOLOGICAL CHEMISTRY, vol. 270, no. 22, 1995, pages 12953 - 12956
Attorney, Agent or Firm:
TSUJII Koichi et al. (JP)
辻居 Koichi (JP)
辻居 Koichi (JP)
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Claims: