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Title:
PHARMACEUTICAL COMPOSITION FOR TREATING EPILEPSY AND CONVULSIONS, INFANTILE CONVULSIONS AND FACIAL SPASMS AND PREPARATION METHOD THEREFOR
Document Type and Number:
WIPO Patent Application WO/2019/205959
Kind Code:
A1
Abstract:
Disclosed are a pharmaceutical composition for treating epilepsy and convulsions, infantile convulsions and facial spasms and a preparation method therefor. The pharmaceutical composition comprises extracts of medicinal materials and auxiliary materials; the extracts of medicinal materials are prepared from Astragali radix, Codonopsis radix, Salviae miltiorrhizae radix et rhizoma, Bupleuri radix, Ziziphi spinosae semen, Polygalae radix, Gastrodiae rhizoma, Uncariae ramulus cum uncis, Acori tatarinowii rhizoma, Arisaema cum bile, Angelicae sinensis radix, Bombyx batryticatus, Massa medicata fermentata, Curcumae radix, Glycyrrhizae radix et rhizoma and prepared Typhonii rhizoma; and the auxiliary materials are calcium carbonate and/or calcium hydrogen phosphate, with an amount of 10 wt% of the extracts of medicinal materials. The hygroscopicity of drugs can be improved, the loading quantity difference of capsules can be reduced, and the long-term stability of capsules can be enhanced.

Inventors:
LV, Huifeng (Mingwu Zhu, 11/F Building B, Huixin IBC, No.1, Zhangba First Road, Hi-tech Industry Development Zon, Xi'an Shaanxi 5, 710065, CN)
HU, Xiaoyan (Mingwu Zhu, 11/F Building B, Huixin IBC, No.1, Zhangba First Road, Hi-tech Industry Development Zon, Xi'an Shaanxi 5, 710065, CN)
Application Number:
CN2019/082398
Publication Date:
October 31, 2019
Filing Date:
April 12, 2019
Export Citation:
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Assignee:
XI' AN CHIHO PHARMACEUTICAL CO., LTD. (Mingwu Zhu, 11/F Building B, Huixin IBC, No.1, Zhangba First Road, Hi-tech Industry Development Zon, Xi'an Shaanxi 5, 710065, CN)
International Classes:
A61K47/02; A61K35/64; A61K36/00; A61K36/232; A61K36/233; A61K36/344; A61K36/481; A61K36/484; A61K36/537; A61K36/69; A61K36/725; A61K36/74; A61K36/888; A61K36/8884; A61K36/8988; A61K36/9066; A61P21/02; A61P25/08
Foreign References:
CN108420994A2018-08-21
CN103033587A2013-04-10
CN104547882A2015-04-29
CN1785409A2006-06-14
CN1857694A2006-11-08
Other References:
JI, FENGHAI ET AL.: "Clinical Observation of Xianyu Capsules Combined with Magnesium Valproate in Treatment of Epilepsy", DRUGS & CLINIC, vol. 33, no. 4, 19 April 2018 (2018-04-19), pages 750 - 753
Attorney, Agent or Firm:
XI’AN YINUO PATENT AGENCY CO, LTD (Process Department, Floor 7 Block D, Wangdu, No.3, Zhangba 1rd, Yant, XI'an Shaanxi 5, 710065, CN)
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