PHARMACEUTICAL COMPOSITION FOR TREATING EPILEPSY AND CONVULSIONS, INFANTILE CONVULSIONS AND FACIAL SPASMS AND PREPARATION METHOD THEREFOR

Title:

PHARMACEUTICAL COMPOSITION FOR TREATING EPILEPSY AND CONVULSIONS, INFANTILE CONVULSIONS AND FACIAL SPASMS AND PREPARATION METHOD THEREFOR

Document Type and Number:

WIPO Patent Application WO/2019/205959

Kind Code:

A1

Abstract:

Disclosed are a pharmaceutical composition for treating epilepsy and convulsions, infantile convulsions and facial spasms and a preparation method therefor. The pharmaceutical composition comprises extracts of medicinal materials and auxiliary materials; the extracts of medicinal materials are prepared from Astragali radix, Codonopsis radix, Salviae miltiorrhizae radix et rhizoma, Bupleuri radix, Ziziphi spinosae semen, Polygalae radix, Gastrodiae rhizoma, Uncariae ramulus cum uncis, Acori tatarinowii rhizoma, Arisaema cum bile, Angelicae sinensis radix, Bombyx batryticatus, Massa medicata fermentata, Curcumae radix, Glycyrrhizae radix et rhizoma and prepared Typhonii rhizoma; and the auxiliary materials are calcium carbonate and/or calcium hydrogen phosphate, with an amount of 10 wt% of the extracts of medicinal materials. The hygroscopicity of drugs can be improved, the loading quantity difference of capsules can be reduced, and the long-term stability of capsules can be enhanced.

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Inventors:

LV HUIFENG (CN)
HU XIAOYAN (CN)

Application Number:

PCT/CN2019/082398

Publication Date:

October 31, 2019

Filing Date:

April 12, 2019

Export Citation:

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Assignee:

XI AN CHIHO PHARMACEUTICAL CO LTD (CN)

International Classes:

A61K47/02; A61K35/64; A61K36/00; A61K36/232; A61K36/233; A61K36/344; A61K36/481; A61K36/484; A61K36/537; A61K36/69; A61K36/725; A61K36/74; A61K36/888; A61K36/8884; A61K36/8988; A61K36/9066; A61P21/02; A61P25/08

Foreign References:

CN108420994A	2018-08-21
CN103033587A	2013-04-10
CN104547882A	2015-04-29
CN1785409A	2006-06-14
CN1857694A	2006-11-08

Other References:

JI, FENGHAI ET AL.: "Clinical Observation of Xianyu Capsules Combined with Magnesium Valproate in Treatment of Epilepsy", DRUGS & CLINIC, vol. 33, no. 4, 19 April 2018 (2018-04-19), pages 750 - 753

Attorney, Agent or Firm:

XI’AN YINUO PATENT AGENCY CO, LTD (CN)

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