Title:
PHARMACEUTICAL COMPOSITION FOR TREATING THE GASTROINTESTINAL TRACT
Document Type and Number:
WIPO Patent Application WO/2011/099000
Kind Code:
A3
Abstract:
The invention provides pharmaceutical compositions for the treatment or prophylaxis of a gastrointestinal tract. In one embodiment, the pharmaceutical composition includes co-particles of an adsorbent, such as active charcoal, and one or more carbohydrates, such as dextrose. This embodiment of the pharmaceutical composition may be used, for example, in the treatment or prophylaxis of diarrhea, for adsorbing digestive tract microorganisms, for enhancing weight gain, or for enhancing milk production in a mammal. In another embodiment of the invention, the pharmaceutical composition includes one or more enzymes and a pH buffer system, wherein the pH buffer system causes an alkalinization of at least a portion of a gastrointestinal tract. This embodiment of the pharmaceutical composition of the invention may be used, for example, for increasing milk production in a mammal.
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Inventors:
SMOLER ELIEZER (IL)
Application Number:
PCT/IL2011/000139
Publication Date:
September 29, 2011
Filing Date:
February 09, 2011
Export Citation:
Assignee:
SMOLER ELIEZER (IL)
International Classes:
A23K1/16; A23K1/175; A23K1/18; A61P1/00
Foreign References:
| US20080248088A1 | 2008-10-09 | |||
| US6294189B1 | 2001-09-25 | |||
| US5795586A | 1998-08-18 |
Other References:
DATABASE CA [online] CHEMICAL ABSTRACTS SERVICE, COLUMBUS, OHIO, US; 2008, MYUNG, YOON-AH ET AL: "Effect of antibiotic substrate(antacid-100) on performance of dairy", XP002637219, retrieved from STN Database accession no. 2008:1542099
TORREGROSA-MACIA R ET AL: "Porous texture of activated carbons modified with carbohydrates", CARBON, ELSEVIER, OXFORD, GB, vol. 35, no. 4, 1 January 1997 (1997-01-01), pages 447 - 453, XP004058446, ISSN: 0008-6223, DOI: DOI:10.1016/S0008-6223(97)83724-4
DATABASE BIOSIS [online] BIOSCIENCES INFORMATION SERVICE, PHILADELPHIA, PA, US; February 2004 (2004-02-01), SENTURK SEZGIN ET AL: "Salt poisoning in beef cattle.", XP002637220, Database accession no. PREV200400165396
RAMOS A-J ET AL: "PREVENTION OF TOXIC EFFECTS OF MYCOTOXINS BY MEANS OF NONNUTRITIVE ADSORBENT COMPOUNDS", JOURNAL OF FOOD PROTECTION, INTERNATIONAL ASSOCIATION FOR FOOD PROTECTION, US, vol. 59, no. 6, 1 January 1996 (1996-01-01), pages 631 - 641, XP008055723, ISSN: 0362-028X
WATARAI S ET AL: "Feeding Activated Charcoal from Bark Containing Wood Vinegar Liquid (Nekka-Rich) Is Effective as Treatment for Cryptosporidiosis in Calves", JOURNAL OF DAIRY SCIENCE, AMERICAN DAIRY SCIENCE ASSOCIATION, US, vol. 91, no. 4, 1 April 2008 (2008-04-01), pages 1458 - 1463, XP026956498, ISSN: 0022-0302, [retrieved on 20080401]
DATABASE BIOSIS [online] BIOSCIENCES INFORMATION SERVICE, PHILADELPHIA, PA, US; 1995, GARILLO E P ET AL: "Effects of activated carbon on growth, ruminal characteristics, blood profiles and feed digestibility in sheep", XP002637221, Database accession no. PREV199598229352
DATABASE CABA [online] 1997, ALI, M. K. ET AL: "Efficacy of certain drug treatments in Lantana camara poisoning in", XP002637222, retrieved from STN Database accession no. 1997:81276
DATABASE CABA [online] 2001, SINGH, P. J. ET AL: "Organochlorine insecticide (Endocel) poisoning in bovine - a clinical", XP002637223, retrieved from STN Database accession no. 2001:113233
TORREGROSA-MACIA R ET AL: "Porous texture of activated carbons modified with carbohydrates", CARBON, ELSEVIER, OXFORD, GB, vol. 35, no. 4, 1 January 1997 (1997-01-01), pages 447 - 453, XP004058446, ISSN: 0008-6223, DOI: DOI:10.1016/S0008-6223(97)83724-4
DATABASE BIOSIS [online] BIOSCIENCES INFORMATION SERVICE, PHILADELPHIA, PA, US; February 2004 (2004-02-01), SENTURK SEZGIN ET AL: "Salt poisoning in beef cattle.", XP002637220, Database accession no. PREV200400165396
RAMOS A-J ET AL: "PREVENTION OF TOXIC EFFECTS OF MYCOTOXINS BY MEANS OF NONNUTRITIVE ADSORBENT COMPOUNDS", JOURNAL OF FOOD PROTECTION, INTERNATIONAL ASSOCIATION FOR FOOD PROTECTION, US, vol. 59, no. 6, 1 January 1996 (1996-01-01), pages 631 - 641, XP008055723, ISSN: 0362-028X
WATARAI S ET AL: "Feeding Activated Charcoal from Bark Containing Wood Vinegar Liquid (Nekka-Rich) Is Effective as Treatment for Cryptosporidiosis in Calves", JOURNAL OF DAIRY SCIENCE, AMERICAN DAIRY SCIENCE ASSOCIATION, US, vol. 91, no. 4, 1 April 2008 (2008-04-01), pages 1458 - 1463, XP026956498, ISSN: 0022-0302, [retrieved on 20080401]
DATABASE BIOSIS [online] BIOSCIENCES INFORMATION SERVICE, PHILADELPHIA, PA, US; 1995, GARILLO E P ET AL: "Effects of activated carbon on growth, ruminal characteristics, blood profiles and feed digestibility in sheep", XP002637221, Database accession no. PREV199598229352
DATABASE CABA [online] 1997, ALI, M. K. ET AL: "Efficacy of certain drug treatments in Lantana camara poisoning in", XP002637222, retrieved from STN Database accession no. 1997:81276
DATABASE CABA [online] 2001, SINGH, P. J. ET AL: "Organochlorine insecticide (Endocel) poisoning in bovine - a clinical", XP002637223, retrieved from STN Database accession no. 2001:113233
Attorney, Agent or Firm:
REINHOLD COHN AND PARTNERS (61131 Tel Aviv, IL)
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