Title:
PHARMACEUTICAL COMPOSITION FOR TREATING OR PREVENTING CANCER
Document Type and Number:
WIPO Patent Application WO/2012/008765
Kind Code:
A3
Abstract:
The present invention relates to the compound of chemical formula I, to the pharmaceutically acceptable salts thereof or hydrates thereof, to a pharmaceutical composition containing the compound as an active ingredient for treating or preventing cancer, and to a method for preparing the compound of chemical formula I.
Inventors:
LEE GEE-HWOON (KR)
Application Number:
PCT/KR2011/005170
Publication Date:
May 31, 2012
Filing Date:
July 13, 2011
Export Citation:
Assignee:
LEE GEE-HWOON (KR)
International Classes:
C07D309/32; A61K31/351; A61P35/00; C07D309/28; C07D309/30
Foreign References:
| KR20090085455A | 2009-08-07 | |||
| US20070167515A1 | 2007-07-19 |
Other References:
GOEL, ATUL ET AL.: "A vicarious synthesis of unsymmetrical meta- and paraterphenyls from 2H-pyran-2-ones.", TETRAHEDRON LETTERS, vol. 46, 2005, pages 8487 - 8491
KASAPLAR, PINAR ET AL.: "6-Bicycloaryl substituted (S)- and (R)-5,6-dihydro-2H-pyran-2-ones: Asymmetric synthesis, and anti-proliferative properties.", BIOORGANIC & MEDICINAL CHEMISTRY, vol. 17, 2009, pages 311 - 318, XP025876000, DOI: doi:10.1016/j.bmc.2008.10.069
NARASIMHULU, MANCHALA ET AL.: "Stereoselective synthesis of (6S) and (6R)-5,6-dihydro-6- [(2R)-2-hydroxy-6-phenylhexyl]-2H-pyran-2-one and their cytotoxic activity against cancer cell lines.", TETRAHEDRON, vol. 65, 2009, pages 2989 - 2994, XP025970406, DOI: doi:10.1016/j.tet.2009.01.101
KASAPLAR, PINAR ET AL.: "6-Bicycloaryl substituted (S)- and (R)-5,6-dihydro-2H-pyran-2-ones: Asymmetric synthesis, and anti-proliferative properties.", BIOORGANIC & MEDICINAL CHEMISTRY, vol. 17, 2009, pages 311 - 318, XP025876000, DOI: doi:10.1016/j.bmc.2008.10.069
NARASIMHULU, MANCHALA ET AL.: "Stereoselective synthesis of (6S) and (6R)-5,6-dihydro-6- [(2R)-2-hydroxy-6-phenylhexyl]-2H-pyran-2-one and their cytotoxic activity against cancer cell lines.", TETRAHEDRON, vol. 65, 2009, pages 2989 - 2994, XP025970406, DOI: doi:10.1016/j.tet.2009.01.101
Attorney, Agent or Firm:
ORIGIN PATENT & LAW FIRM (Yeoksam-dongKangnam-ku, Seoul 135-908, KR)
Download PDF:
Claims: