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Title:
PHARMACEUTICAL COMPOSITION FOR TREATING AND/OR PREVENTING CANCER
Document Type and Number:
WIPO Patent Application WO/2023/033129
Kind Code:
A1
Abstract:
In the present invention, by linking dolastatin 10 or a derivative thereof to an antibody or fragment thereof having immunological reactivity with CAPRIN-1 protein having an amino acid sequence shown in any one of the even numbered SEQ ID NOs: 2 to 30 or an amino acid sequence having 80% or more sequence identity with such amino acid sequence, the anti-tumoral effect by such antibody or such fragment thereof is enhanced.

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Inventors:
OKANO FUMIYOSHI (JP)
SAITO TAKANORI (JP)
Application Number:
PCT/JP2022/033055
Publication Date:
March 09, 2023
Filing Date:
September 02, 2022
Export Citation:
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Assignee:
TORAY INDUSTRIES (JP)
International Classes:
A61K47/68; A61K38/08; A61K39/395; A61P35/00; A61P35/02; C07K7/06; C07K16/28; C07K16/30; C07K16/46; C07K19/00; C12N15/13; C12N15/62; C12P21/08
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