PHARMACEUTICAL COMPOSITION FOR TREATING OR PREVENTING DISEASES CAUSED BY THE NUCLEAR EXPORT OF GSK3, INCLUDING A COMPOUND FOR INHIBITING THE NUCLEAR EXPORT OF GSK3

Title:

PHARMACEUTICAL COMPOSITION FOR TREATING OR PREVENTING DISEASES CAUSED BY THE NUCLEAR EXPORT OF GSK3, INCLUDING A COMPOUND FOR INHIBITING THE NUCLEAR EXPORT OF GSK3

Document Type and Number:

WIPO Patent Application WO/2011/111880

Kind Code:

A1

Abstract:

The present invention relates to a pharmaceutical composition for treating or preventing disease caused by the nuclear export of GSK3, including a compound for inhibiting the nuclear export of GSK3, and more specifically, to a pharmaceutical composition for inhibiting the growth or metastasis of cancer cells and including a novel compound for inhibiting the nuclear export of GSK3, and to a pharmaceutical composition for treating autoimmune diseases. According to the present invention, a composition for inhibiting the onset and progression of a disease caused by a decrease in GSK3 concentration in a cell nucleus through the nuclear export of GSK3 is provided. The compound according to the present invention is useful for treating or preventing various diseases by inhibiting the nuclear export function of GSK3 by Axin and increasing the concentration of GSK3 in the nucleus.

More Like This:

WO/1995/033464	RETROVIRAL PROTEASE INHIBITOR COMBINATIONS
JPH10510512	INDUSTRIAL APPLICABILITY [Title of Invention] Use as a urea derivative and an ACAT inhibitor
JP5492764	Substituted sulfonamides, methods of their production, pharmaceutical compositions containing them and their use

Inventors:

YOOK JONG IN (KR)
KIM HYUN SIL (KR)
KIM NAM HEE (KR)
NO KYOUNG TAI (KR)
KIM SU YEON (KR)

Application Number:

PCT/KR2010/001445

Publication Date:

September 15, 2011

Filing Date:

March 08, 2010

Export Citation:

Click for automatic bibliography generation Help

Assignee:

MEDIGENTEK CO LTD (KR)
BIOINFORMATICS & MOLECULAR DESIGN RES CT (KR)
YOOK JONG IN (KR)
KIM HYUN SIL (KR)
KIM NAM HEE (KR)
NO KYOUNG TAI (KR)
KIM SU YEON (KR)

International Classes:

A61K31/18; A61K31/4196; A61K31/4439; A61K31/47; A61K31/4738; A61K31/519; A61P35/00

Foreign References:

US20070129364A1	2007-06-07
US20060211678A1	2006-09-21
US20060069097A1	2006-03-30

Attorney, Agent or Firm:

LEE, Cheo Young (KR)
이처영 (KR)

Download PDF:

View/Download PDF PDF Help

Claims:

Previous Patent: FLUIDIZED MEMBRANE BIOREACTOR

Next Patent: BIODEGRADABLE RAZOR HANDLE, METHOD FOR MANUFACTURING SAME, AND RAZOR INCLUDING A BIODEGRADABLE RAZOR...