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Title:
PHARMACEUTICAL COMPOSITION FOR TREATING OR PREVENTING GLAUCOMA
Document Type and Number:
WIPO Patent Application WO/2010/113957
Kind Code:
A1
Abstract:
Provided is a pharmaceutical composition for treating or preventing glaucoma, comprising a pyridylamino acetic acid compound represented by general formula (1) or a pharmacologically acceptable salt thereof as an active ingredient. In formula (1), R1, R2, and R3 each independently represent a hydrogen atom or the like; Y represents a group: -Q1-Q2 (wherein Q1 represents an arylene group or the like; and Q2 represents a group such as an aromatic ring group which may be substituted by a halogen atom or the like) or a dicyclic heteroaromatic ring which may be substituted by a halogen atom or the like; and Z represents a group such as an aromatic ring group which may be substituted by a halogen atom or the like.

Inventors:
HAGIHARA MASAHIKO
YONEDA KENJI
OKANARI EIJI
SHIGETOMI MANABU
Application Number:
PCT/JP2010/055719
Publication Date:
October 07, 2010
Filing Date:
March 30, 2010
Export Citation:
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Assignee:
UBE INDUSTRIES (JP)
HAGIHARA MASAHIKO
YONEDA KENJI
OKANARI EIJI
SHIGETOMI MANABU
International Classes:
C07D213/83; A61K31/44; A61K31/443; A61K31/4439; A61K31/444; A61K31/501; A61K31/506; A61P27/06; C07D401/12; C07D405/14; C07D409/14; C07D417/12; C07D417/14; C07D401/14
Domestic Patent References:
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Foreign References:
JP2006519250A2006-08-24
JP2008503490A2008-02-07
US20070000939A12007-01-04
JP2001519414A2001-10-23
Other References:
CHRISTOPHER P. HOLMES, ET AL.: "PTP1B inhibitors: Synthesis and evaluation of difluoro-methylenephosphonate bioisosteres on a sulfonamide scaffold", BIOORG.MED.CHEM.LETT., vol. 18, no. 8, 2008, pages 2719 - 2724, XP022606378
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ABRAANOVITZ ET AL., BIOCHIMICA ET BIOPHYSICA ACTA, vol. 1483, 2000, pages 285
WILSON ET AL., EUROPEAN JOURNAL OFPHARMACOLOGY, vol. 501, 2004, pages 49
Attorney, Agent or Firm:
TSUKUNI, HAJIME (JP)
Hajime Tsukuni (JP)
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