Title:
PHARMACEUTICAL COMPOSITION FOR TREATING OR PREVENTING MIDDLE EAST RESPIRATORY SYNDROME
Document Type and Number:
WIPO Patent Application WO/2020/159343
Kind Code:
A1
Abstract:
The present invention relates to an amide derivative compound or a pharmaceutically acceptable salt thereof, which can be beneficially used in the treatment or prevention of Middle East Respiratory Syndrome (MERS). In addition, the present invention relates to a pharmaceutical composition for treating or preventing MERS, comprising said compound or a pharmaceutically acceptable salt thereof.
Inventors:
KU JIN-MO (KR)
JEONG KWI-WAN (KR)
JUNG SEUNG-YOUNG (KR)
JEONG KWI-WAN (KR)
JUNG SEUNG-YOUNG (KR)
Application Number:
PCT/KR2020/001600
Publication Date:
August 06, 2020
Filing Date:
February 03, 2020
Export Citation:
Assignee:
GYEONGGIDO BUSINESS & SCIENCE ACCELERATOR (KR)
International Classes:
C07D239/10; A61K31/513; A61K45/06; A61P31/14; C07D409/08
Foreign References:
| KR100404993B1 | 2004-06-04 | |||
| KR20170123308A | 2017-11-07 |
Other References:
DE WILDE, A. H. ET AL.: "Screening of an FDA-approved Compound Library Identifies Four Small-Molecule Inhibitors of Middle East Respiratory Syndrome Coronavirus Replication in Cell Culture", ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, vol. 58, no. 8, 2014, pages 4875 - 4884, XP055725901, DOI: 10.1128/AAC.03011-14
LIU, QI AND XIA SHUAI, SUN ZHIWU, WANG QIAN, DU LANYING, LU LU, JIANG SHIBO: "Testing of Middle East Respiratory Syndrome Coronavirus Replication Inhibitors for the Ability To Block Viral Entry", ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, vol. 59, no. 1, 2015, pages 742 - 744, XP055729062, DOI: 10.1128/AAC.03977-14
CHAN, JASPER F.-W. AND YAO YANFENG, YEUNG MAN-LUNG, DENG WEI, BAO LINLIN, JIA LILONG, LI FENGDI, XIAO CHONG, GAO HONG, YU PIN, CAI: "Treatment With Lopinavir/Ritonavir or Interferon-beta1b Improves Outcome of MERS-Co V Infection in a Nonhuman Primate Model of Common Marmoset", J INFECT DIS., vol. 212, 2015, pages 1904 - 1913, XP055729063
LIU, QI AND XIA SHUAI, SUN ZHIWU, WANG QIAN, DU LANYING, LU LU, JIANG SHIBO: "Testing of Middle East Respiratory Syndrome Coronavirus Replication Inhibitors for the Ability To Block Viral Entry", ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, vol. 59, no. 1, 2015, pages 742 - 744, XP055729062, DOI: 10.1128/AAC.03977-14
CHAN, JASPER F.-W. AND YAO YANFENG, YEUNG MAN-LUNG, DENG WEI, BAO LINLIN, JIA LILONG, LI FENGDI, XIAO CHONG, GAO HONG, YU PIN, CAI: "Treatment With Lopinavir/Ritonavir or Interferon-beta1b Improves Outcome of MERS-Co V Infection in a Nonhuman Primate Model of Common Marmoset", J INFECT DIS., vol. 212, 2015, pages 1904 - 1913, XP055729063
Attorney, Agent or Firm:
IPSCENT (KR)
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