Title:
PHARMACEUTICAL COMPOSITION FOR TREATMENT AND/OR PREVENTION OF GALL BLADDER CANCER
Document Type and Number:
WIPO Patent Application WO/2013/147176
Kind Code:
A1
Abstract:
Provided is antibody effective for the treatment and/or prevention of gall bladder cancer. A pharmaceutical composition for the treatment and/or prevention of gall bladder cancer, including as an effective component thereof: an antibody having immunological reactivity to a CAPRIN-1 protein or a fragment thereof including at least seven continuous amino acid resides in an amino acid array of said protein; or a fragment thereof.
Inventors:
SAITO TAKANORI (JP)
OKANO FUMIYOSHI (JP)
IDO TAKAYOSHI (JP)
OKANO FUMIYOSHI (JP)
IDO TAKAYOSHI (JP)
Application Number:
PCT/JP2013/059569
Publication Date:
October 03, 2013
Filing Date:
March 29, 2013
Export Citation:
Assignee:
TORAY INDUSTRIES (JP)
International Classes:
A61K39/395; A61P35/00; C07K16/18; C07K16/46; C12N15/09
Domestic Patent References:
| WO2010016526A1 | 2010-02-11 | |||
| WO2010016525A1 | 2010-02-11 | |||
| WO2010016527A1 | 2010-02-11 | |||
| WO2011096535A1 | 2011-08-11 | |||
| WO2013018885A1 | 2013-02-07 | |||
| WO2013018886A1 | 2013-02-07 | |||
| WO2010016526A1 | 2010-02-11 | |||
| WO2002043478A2 | 2002-06-06 | |||
| WO2002092812A1 | 2002-11-21 | |||
| WO1998046777A1 | 1998-10-22 | |||
| WO1996002576A1 | 1996-02-01 | |||
| WO1999051743A1 | 1999-10-14 | |||
| WO2011096528A1 | 2011-08-11 | |||
| WO2011096519A1 | 2011-08-11 | |||
| WO2011096517A1 | 2011-08-11 | |||
| WO2011096533A1 | 2011-08-11 | |||
| WO2011096534A1 | 2011-08-11 | |||
| WO2013018894A1 | 2013-02-07 | |||
| WO2013018892A1 | 2013-02-07 | |||
| WO2013018891A1 | 2013-02-07 | |||
| WO2013018889A1 | 2013-02-07 | |||
| WO2013018883A1 | 2013-02-07 |
Foreign References:
| JP2012080780A | 2012-04-26 | |||
| JP2007530068A | 2007-11-01 | |||
| EP0239400A2 | 1987-09-30 |
Other References:
KADDER T. ET AL.: "Two new miR-16 targets: caprin-1 and HMGA1, proteins implicated in cell proliferation", BIOLOGY OF THE CELL, vol. 101, 2009, pages 511 - 524, XP008167708
KARLIN; ALTSCHUL, PROC. NATL. ACAD. SCI. USA, vol. 90, 1993, pages 5873 - 5877
ALTSCHUL ET AL., NUCLEIC ACIDS RES., vol. 25, 1997, pages 3389 - 3402
"Seikagaku Jikken Koza", 1981, TOKYO KAGAKU DOJIN, article "Kagaku shushoku to peputido gosei"
SAMBROOK ET AL.: "Current Protocols in Molecular Biology", 1989, COLD SPRING HARBOR LABORATORY PRESS, article "Molecular Cloning"
AUSUBEL ET AL.: "Short Protocols in Molecular Biology", 1995, JOHN WILEY & SONS, article "A compendium of Methods from Current Protocols in Molecular Biology"
SAMBROOK ET AL.: "Molecular Cloning", 1989, article "Current Protocols in Molecular Biology"
J. IMMUNOL., vol. 123, 1979, pages 1548 - 1550
CURRENT TOPICS IN MICROBIOLOGY AND IMMUNOLOGY, vol. 81, 1978, pages 1 - 7
KOHLER, G.; MILSTEIN, C., EUR. J. IMMUNEL, vol. 6, 1976, pages 511 - 519
MARGULIES, D.H. ET AL., CELL
SHULMAN, M. ET AL., NATURE, vol. 276, 1978, pages 269 - 270
GROTH, S.F. ET AL., J. IMMUNOL. METHODS, vol. 35, 1980, pages 1 - 21
TROWBRIDGE, I.S., J. EXP. MED., vol. 148, 1978, pages 313 - 323
GALFRE, G. ET AL., NATURE, vol. 277, 1979, pages 131 - 133
KOHLER, G.; MILSTEIN, C., METHODS ENZYMOL., vol. 73, 1981, pages 3 - 46
CARL, A.K. BORREBAECK; JAMES, W. LARRICK: "THERAPEUTIC MONOCLONAL ANTIBODIES", 1990, MACMILLAN PUBLISHERS LTD
SATO K. ET AL., CANCER RESEARCH, vol. 53, 1993, pages 851 - 856
GENE, vol. 152, 1995, pages 271 - 275
ZOLLER, M.J.; SMITH, M., METHODS ENZYMOL., vol. 100, 1983, pages 468 - 500
KRAMER, W. ET AL., NUCLEIC ACIDS RES., vol. 12, 1984, pages 9441 - 9456
KRAMER, W.; FRITZ, H.J., METHODS ENZYMOL., vol. 154, 1987, pages 350 - 367
KUNKEL, TA., PROC. NATL. ACAD. SCI. USA., vol. 82, 1985, pages 488 - 492
KUNKEL, METHODS ENZYMOL., vol. 85, 1988, pages 2763 - 2766
KABAT ET AL.: "Sequences of Proteins of Immunological Interest", 1991, NATIONAL INSTITUTE OF HEALTH
SAMBROOK ET AL.: "Molecular Cloning A Laboratory Manual", 1989, COLD SPRING HARBOR LABORATORY PRESS
G. -B. KIM ET AL., PROTEIN ENGINEERING DESIGN AND SELECTION, vol. 20, no. 9, 2007, pages 425 - 432
P.J. DELVES., ANTIBODY PRODUCTION ESSENTIAL TECHNIQUES, 1997
WILEY, P. SHEPHERD; C. DEAN.: "onoclonal Antibodies", 2000, OXFORD UNIVERSITY PRESS
J.W. GODING.: "Monoclonal Antibodies: principles and practice", 1993, ACADEMIC PRESS
JONES, S.T.; BENDING, M.M., BIO/TECHNOLOGY, vol. 9, 1991, pages 88 - 89
See also references of EP 2832366A4
KARLIN; ALTSCHUL, PROC. NATL. ACAD. SCI. USA, vol. 90, 1993, pages 5873 - 5877
ALTSCHUL ET AL., NUCLEIC ACIDS RES., vol. 25, 1997, pages 3389 - 3402
"Seikagaku Jikken Koza", 1981, TOKYO KAGAKU DOJIN, article "Kagaku shushoku to peputido gosei"
SAMBROOK ET AL.: "Current Protocols in Molecular Biology", 1989, COLD SPRING HARBOR LABORATORY PRESS, article "Molecular Cloning"
AUSUBEL ET AL.: "Short Protocols in Molecular Biology", 1995, JOHN WILEY & SONS, article "A compendium of Methods from Current Protocols in Molecular Biology"
SAMBROOK ET AL.: "Molecular Cloning", 1989, article "Current Protocols in Molecular Biology"
J. IMMUNOL., vol. 123, 1979, pages 1548 - 1550
CURRENT TOPICS IN MICROBIOLOGY AND IMMUNOLOGY, vol. 81, 1978, pages 1 - 7
KOHLER, G.; MILSTEIN, C., EUR. J. IMMUNEL, vol. 6, 1976, pages 511 - 519
MARGULIES, D.H. ET AL., CELL
SHULMAN, M. ET AL., NATURE, vol. 276, 1978, pages 269 - 270
GROTH, S.F. ET AL., J. IMMUNOL. METHODS, vol. 35, 1980, pages 1 - 21
TROWBRIDGE, I.S., J. EXP. MED., vol. 148, 1978, pages 313 - 323
GALFRE, G. ET AL., NATURE, vol. 277, 1979, pages 131 - 133
KOHLER, G.; MILSTEIN, C., METHODS ENZYMOL., vol. 73, 1981, pages 3 - 46
CARL, A.K. BORREBAECK; JAMES, W. LARRICK: "THERAPEUTIC MONOCLONAL ANTIBODIES", 1990, MACMILLAN PUBLISHERS LTD
SATO K. ET AL., CANCER RESEARCH, vol. 53, 1993, pages 851 - 856
GENE, vol. 152, 1995, pages 271 - 275
ZOLLER, M.J.; SMITH, M., METHODS ENZYMOL., vol. 100, 1983, pages 468 - 500
KRAMER, W. ET AL., NUCLEIC ACIDS RES., vol. 12, 1984, pages 9441 - 9456
KRAMER, W.; FRITZ, H.J., METHODS ENZYMOL., vol. 154, 1987, pages 350 - 367
KUNKEL, TA., PROC. NATL. ACAD. SCI. USA., vol. 82, 1985, pages 488 - 492
KUNKEL, METHODS ENZYMOL., vol. 85, 1988, pages 2763 - 2766
KABAT ET AL.: "Sequences of Proteins of Immunological Interest", 1991, NATIONAL INSTITUTE OF HEALTH
SAMBROOK ET AL.: "Molecular Cloning A Laboratory Manual", 1989, COLD SPRING HARBOR LABORATORY PRESS
G. -B. KIM ET AL., PROTEIN ENGINEERING DESIGN AND SELECTION, vol. 20, no. 9, 2007, pages 425 - 432
P.J. DELVES., ANTIBODY PRODUCTION ESSENTIAL TECHNIQUES, 1997
WILEY, P. SHEPHERD; C. DEAN.: "onoclonal Antibodies", 2000, OXFORD UNIVERSITY PRESS
J.W. GODING.: "Monoclonal Antibodies: principles and practice", 1993, ACADEMIC PRESS
JONES, S.T.; BENDING, M.M., BIO/TECHNOLOGY, vol. 9, 1991, pages 88 - 89
See also references of EP 2832366A4
Attorney, Agent or Firm:
HIRAKI Yusuke et al. (JP)
Yusuke Hiraki (JP)
Yusuke Hiraki (JP)
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