PHARMACEUTICAL CREAM COMPOSITIONS COMPRISING OXYMETAZOLINE

Title:

PHARMACEUTICAL CREAM COMPOSITIONS COMPRISING OXYMETAZOLINE

Document Type and Number:

WIPO Patent Application WO/2012/075319

Kind Code:

A3

Abstract:

Embodiments relating to cream formulations as well as oxymetazoline creams and methods for treating rosacea and symptoms associated with rosacea, including, for example, papules, pustules, phymas (skin thickening), telangiectasias or erythema associated with rosacea, other skin erythemas, telangiectasias, purpura or the like, and other manifestations associated therewith; other inflammatory conditions of the skin including, but not limited to, keratosis pilaris, lupus miliaris dissemniatus faciei, eczema, dermatitis, such as contact dermatitis, atopic dermatitis, seborrheic dermatitis, nummular dermatitis, generalized exfoliative dermatitis, statis dermatitis, neurodermatitis, lichen simplex chronicus, xerosis and xerotic dermatitis, dyshidrosis and dyshidrotic dermatitis, asteototic dermatitis or other conditions characterized by sensitive skin or a disturbance of the epidermal barrier; disorders characterized by rough, dry, cracked or fissured skin, disorders characterized by hyperkeratotic skin such as keratodermas and ichthyosisis and ichthyosiform dermatoses; disorders of hair follicles and sebaceous glands, such as acne, perioral dermatitis, and pseudofolliculitis barbae; disorders of sweat glands, such as miliaria, including, but not limited to, miliaria crystallina, miliaria rubra, miliaria profunda, miliaria pustulosa; sunburn, chronic actinic damage, poikiloderma, radiation dermatitis, actinic purpura ("solar purpura"); other inflammatory dermatoses, reactions and conditions of the skin, including, but not limited to, psoriasis, drug eruptions, erythema multiforme, erythema nodosum, and granuloma annulare; diseases and conditions characterized by bleeding or bruising such as petechiae, ecchymosis, purpura and the like including any accumulation of blood in the skin due to vascular extravasation, irrespective of size or cause, bleeding or bruising due to any skin injury which may include any trauma including surgical or procedural trauma; infection, inflammatory dermatoses or inflammation due to any cause using such creams are described herein.

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Inventors:

SHANLER STUART D (US)
POWALA CHRISTOPHER (US)
RIOS LUIS (US)

Application Number:

PCT/US2011/062936

Publication Date:

July 19, 2012

Filing Date:

December 01, 2011

Export Citation:

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Assignee:

ALLERGAN INC (US)
SHANLER STUART D (US)
POWALA CHRISTOPHER (US)
RIOS LUIS (US)

International Classes:

A61K9/10; A61K9/00; A61K31/4174; A61K47/10; A61K47/14

Domestic Patent References:

WO2009065116A1	2009-05-22
WO2012047645A2	2012-04-12

Foreign References:

US20070065390A1	2007-03-22
US20050165079A1	2005-07-28
US3670087A	1972-06-13

Attorney, Agent or Firm:

CHAN, Ted A. et al. (Inc.2525 Dupont Driv, Irvine California, US)

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