Title:
PHARMACEUTICAL OR FOOD CONTAINING PEPTIDE
Document Type and Number:
WIPO Patent Application WO/2013/129220
Kind Code:
A1
Abstract:
The present invention provides a pharmaceutical, pharmaceutical composition, or food in which a dipeptide comprising Met (M) or an analog thereof and His (H) or an analog thereof is an active ingredient, as well as a method and use for preventing or treating a disease such as a lifestyle disease.
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Inventors:
OHINATA KOUSAKU (JP)
YAMADA AYAKO (JP)
MIZUSHIGE TAKAFUMI (JP)
YAMADA AYAKO (JP)
MIZUSHIGE TAKAFUMI (JP)
Application Number:
PCT/JP2013/054289
Publication Date:
September 06, 2013
Filing Date:
February 21, 2013
Export Citation:
Assignee:
UNIV KYOTO (JP)
International Classes:
A61K38/00; A23L1/305; A61P3/00; A61P3/06; A61P3/10; A61P25/18; A61P25/20; A61P25/22; A61P25/24; C07K5/06
Domestic Patent References:
| WO2010114275A2 | 2010-10-07 |
Foreign References:
| EP2161028A1 | 2010-03-10 | |||
| EP2161029A1 | 2010-03-10 | |||
| JP2008297208A | 2008-12-11 | |||
| US20100247707A1 | 2010-09-30 | |||
| EP2490021A1 | 2012-08-22 |
Other References:
ONO, S. ET AL.: "Isolation of peptides with angiotensin I-converting enzyme inhibitory effect derived from hydrolysate of upstream chum salmon muscle", JOURNAL OF FOOD SCIENCE, vol. 68, no. 5, 2003, pages 1611 - 1614, XP002603461
KANEGAWA, N. ET AL.: "Dipeptide Tyr-Leu (YL) exhibits anxiolytic-like activity after oral administration via activating serotonin 5-HTlA, dopamine D1 and GABAA receptors in mice", FEBS LETTERS, vol. 584, no. 3, 2010, pages 599 - 604, XP026865081
OJHA, S.K. ET AL.: "Effect of buspirone: an anxiolytic drug on blood glucose in humans", INDIAN JOURNAL OF CLINICAL BIOCHEMISTRY, vol. 21, no. 2, 2006, pages 58 - 62
DEPOORTERE, R. ET AL.: "SSR181507, A Dopamine D2 Receptor Antagonist and 5-HTlA Receptor Agonist. II: Behavioral Profile Predictive of an Atypical Antipsychotic Activity", NEUROPSYCHOPHARMACOLOGY, vol. 28, no. 11, 2003, pages 1889 - 1902
KANEGAWA, N. ET AL.: "Dipeptide Tyr-Leu (YL) exhibits anxiolytic-like activity after oral administration via activating serotonin 5-HTlA, dopamine D1 and GABAA receptors in mice", FEBS LETTERS, vol. 584, no. 3, 2010, pages 599 - 604, XP026865081
OJHA, S.K. ET AL.: "Effect of buspirone: an anxiolytic drug on blood glucose in humans", INDIAN JOURNAL OF CLINICAL BIOCHEMISTRY, vol. 21, no. 2, 2006, pages 58 - 62
DEPOORTERE, R. ET AL.: "SSR181507, A Dopamine D2 Receptor Antagonist and 5-HTlA Receptor Agonist. II: Behavioral Profile Predictive of an Atypical Antipsychotic Activity", NEUROPSYCHOPHARMACOLOGY, vol. 28, no. 11, 2003, pages 1889 - 1902
Attorney, Agent or Firm:
SAEGUSA & PARTNERS (JP)
Patent business corporation 3 Edakuni [Hajime] patent firm (JP)
Patent business corporation 3 Edakuni [Hajime] patent firm (JP)
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Claims: