Title:
PHARMACEUTICAL PREPARATION, FOOD OR BEVERAGE HAVING INHIBITORY ACTIVITY ON SEROTONIN TRANSPORTER
Document Type and Number:
WIPO Patent Application WO/2010/021247
Kind Code:
A1
Abstract:
Disclosed is a pharmaceutical preparation, food or beverage for treating or preventing a disease or condition which can be ameliorated through the inhibition of serotonin reuptake. The pharmaceutical preparation, food or beverage comprises a clinically effective amount of (1S,3S)-1-methyl-1,2,3,4-tetrahydro-β-carboline-3- carboxylic acid.
Inventors:
BEPPU YOSHINORI (JP)
TSURUOKA NOBUO (JP)
KOMURA HAJIME (JP)
TSURUOKA NOBUO (JP)
KOMURA HAJIME (JP)
Application Number:
PCT/JP2009/063934
Publication Date:
February 25, 2010
Filing Date:
August 06, 2009
Export Citation:
Assignee:
SUNTORY HOLDINGS LTD (JP)
BEPPU YOSHINORI (JP)
TSURUOKA NOBUO (JP)
KOMURA HAJIME (JP)
BEPPU YOSHINORI (JP)
TSURUOKA NOBUO (JP)
KOMURA HAJIME (JP)
International Classes:
A23L1/30; A61K31/473; A23L33/135; A61K31/475; A61K35/74; A61K35/744; A61K35/745; A61K35/747; A61P25/00; A61P25/24; A61P43/00; C07D471/04
Foreign References:
| JP2004131407A | 2004-04-30 | |||
| JP2002058450A | 2002-02-26 |
Other References:
HERRAIZ, T.: "Identification and occurrence of beta-carboline alkaloids in raisins and inhibition of monoamine oxidase (MAO)", J AGRIC FOOD CHEM, vol. 55, no. 21, 2007, pages 8534 - 8540, XP008142624
HERRAIZ, T. ET AL.: "Analysis of monoamine oxidase enzymatic activity by reversed-phase high performance liquid chromatography and inhibition by beta-carboline alkaloids occurring in foods and plants", J CHROMATOGR A, vol. 1120, no. 1-2, 2006, pages 237 - 243, XP024967229
HERRAIZ, T. ET AL.: "Chemical and technological factors determining tetrahydro-P-carboline-3- carboxylic acid content in fermented alcoholic beverages", J. AGRIC. FOOD CHEM., vol. 41, no. 6, 1993, pages 959 - 964, XP008142638
HERRAIZ, T. ET AL.: "Identification and occurrence of tryptamine-and tryptophan-derived tetrahydro-beta-carbolines in commercial sausages", J AGRIC FOOD CHEM, vol. 52, no. 9, 2004, pages 2652 - 2658, XP008142639
TOSHIKI MORICHI ET AL.: "Biopreservation-Nyusankin ni yoru Shokuhin Biseibutsu Seigyo", KABUSHIKI KAISHA SAIWAI SHOBO, 5 December 1999 (1999-12-05), pages 10 - 3, XP008142635
APA: AM J PSYCHIATRY, vol. 157, no. 4, 2000, pages 1 - 20
PINCUS HA ET AL., ARCH GEN PSYCHIATRY, vol. 56, 1999, pages 442 - 449
SOICHIRO NOMURA: "Report of Commissioned Studies on Disaster Science", MINISTRY OF HEALTH, LABOUR AND WELFARE, 2001
SOICHI NOMURA, BESSATSU NIPPON RINSHO SEISHIN IGAKU SHOKOGUN, vol. 138, 2003, pages 236 - 239
TERUAKI TANAKA ET AL., BESSATSU NIPPON RINSHO SEISHIN IGAKU SHOKOGUN I, vol. 38, 2003, pages 362 - 365
SHIGETO YAMAWAKI ET AL., BESSATSU NIPPON RINSHO SEISHIN IGAKU SHOKOGUN, vol. 138, 2003, pages 370 - 373
TAMAM L ET AL., ADV THER, vol. 19, 2002, pages 17 - 26
HADDAD P, J PSYCHOPHARMACOL, vol. 12, 1996, pages 305 - 313
T. HERRAIZ, J. AGRIC. FOOD CHEM, vol. 47, 1999, pages 4883 - 4887
T. HERRAIZ, J. AGRIC. FOOD CHEM, vol. 44, 1996, pages 3057 - 3065
SHUICHI M ET AL., BIOSCI. BIOTECHNOL. BIOCHEM, vol. 69, 2005, pages 2232 - 2235
TOMAS H ET AL., J. AGRIC. FOOD CHEM, vol. 41, 1993, pages 959 - 964
KOTEPPA P ET AL., J. BIOL. CHEM, vol. 275, 2000, pages 2455 - 2462
PAHKLA R ET AL., PHARMACOL TOXICOL, vol. 80, 1997, pages 122 - 126
PAHKLA R ET AL., PHARMACOL RESEARCH, vol. 34, 1996, pages 73 - 78
MASAHIKO T ET AL., EUROPEAN JOURNAL OF PHARMACOLOGY, vol. 368, 1999, pages 277 - 283
See also references of EP 2332539A4
HERRAIZ, T. ET AL.: "Analysis of monoamine oxidase enzymatic activity by reversed-phase high performance liquid chromatography and inhibition by beta-carboline alkaloids occurring in foods and plants", J CHROMATOGR A, vol. 1120, no. 1-2, 2006, pages 237 - 243, XP024967229
HERRAIZ, T. ET AL.: "Chemical and technological factors determining tetrahydro-P-carboline-3- carboxylic acid content in fermented alcoholic beverages", J. AGRIC. FOOD CHEM., vol. 41, no. 6, 1993, pages 959 - 964, XP008142638
HERRAIZ, T. ET AL.: "Identification and occurrence of tryptamine-and tryptophan-derived tetrahydro-beta-carbolines in commercial sausages", J AGRIC FOOD CHEM, vol. 52, no. 9, 2004, pages 2652 - 2658, XP008142639
TOSHIKI MORICHI ET AL.: "Biopreservation-Nyusankin ni yoru Shokuhin Biseibutsu Seigyo", KABUSHIKI KAISHA SAIWAI SHOBO, 5 December 1999 (1999-12-05), pages 10 - 3, XP008142635
APA: AM J PSYCHIATRY, vol. 157, no. 4, 2000, pages 1 - 20
PINCUS HA ET AL., ARCH GEN PSYCHIATRY, vol. 56, 1999, pages 442 - 449
SOICHIRO NOMURA: "Report of Commissioned Studies on Disaster Science", MINISTRY OF HEALTH, LABOUR AND WELFARE, 2001
SOICHI NOMURA, BESSATSU NIPPON RINSHO SEISHIN IGAKU SHOKOGUN, vol. 138, 2003, pages 236 - 239
TERUAKI TANAKA ET AL., BESSATSU NIPPON RINSHO SEISHIN IGAKU SHOKOGUN I, vol. 38, 2003, pages 362 - 365
SHIGETO YAMAWAKI ET AL., BESSATSU NIPPON RINSHO SEISHIN IGAKU SHOKOGUN, vol. 138, 2003, pages 370 - 373
TAMAM L ET AL., ADV THER, vol. 19, 2002, pages 17 - 26
HADDAD P, J PSYCHOPHARMACOL, vol. 12, 1996, pages 305 - 313
T. HERRAIZ, J. AGRIC. FOOD CHEM, vol. 47, 1999, pages 4883 - 4887
T. HERRAIZ, J. AGRIC. FOOD CHEM, vol. 44, 1996, pages 3057 - 3065
SHUICHI M ET AL., BIOSCI. BIOTECHNOL. BIOCHEM, vol. 69, 2005, pages 2232 - 2235
TOMAS H ET AL., J. AGRIC. FOOD CHEM, vol. 41, 1993, pages 959 - 964
KOTEPPA P ET AL., J. BIOL. CHEM, vol. 275, 2000, pages 2455 - 2462
PAHKLA R ET AL., PHARMACOL TOXICOL, vol. 80, 1997, pages 122 - 126
PAHKLA R ET AL., PHARMACOL RESEARCH, vol. 34, 1996, pages 73 - 78
MASAHIKO T ET AL., EUROPEAN JOURNAL OF PHARMACOLOGY, vol. 368, 1999, pages 277 - 283
See also references of EP 2332539A4
Attorney, Agent or Firm:
ONO, Shinjiro et al. (JP)
Ono Shinjiro (JP)
Ono Shinjiro (JP)
Download PDF:
Previous Patent: GEAR POWER TRANSMITTING DEVICE AND SOLAR GENERATING DEVICE
Next Patent: SEPARATOR FOR NONAQUEOUS SECONDARY BATTERY
Next Patent: SEPARATOR FOR NONAQUEOUS SECONDARY BATTERY