Title:
PHARMACOLOGICAL AGENTS FOR TREATING OCULAR DISEASES
Document Type and Number:
WIPO Patent Application WO/2019/195761
Kind Code:
A3
Abstract:
Methods of treating presbyopia or cataract in a subject in need thereof are provided, The methods require administering to the subject an effective amount of a composition comprising a compound that inhibits the formation of high molecular weight aggregates of human α-A-crystallin. Compositions containing certain compounds are believed to be also effective in the treatment: of transthyretin (TTR)-associated amyloidosis and Parkinson's disease.
Inventors:
DE SURYA (US)
PRASAD G (US)
PETERMAN MARSHALL (US)
COLLINS BERNARD (US)
PRASAD G (US)
PETERMAN MARSHALL (US)
COLLINS BERNARD (US)
Application Number:
PCT/US2019/026112
Publication Date:
July 23, 2020
Filing Date:
April 05, 2019
Export Citation:
Assignee:
CALASIA PHARMACEUTICALS INC (US)
International Classes:
A61K8/35; A61K31/04; A61K31/12; C07C39/04; C07C49/76; C07C205/06
Domestic Patent References:
| WO2017039525A1 | 2017-03-09 |
Foreign References:
| US20150246963A1 | 2015-09-03 | |||
| US5877353A | 1999-03-02 | |||
| US5476875A | 1995-12-19 | |||
| US20110152274A1 | 2011-06-23 |
Attorney, Agent or Firm:
MAHANTA, Sanjeev, K. et al. (US)
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