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Title:
PHARMACOLOGICALLY ACTIVE 4,4'-BIPHENYLAMIDE DERIVATIVES AND DRUGS BASED THEREON
Document Type and Number:
WIPO Patent Application WO/2012/138254
Kind Code:
A3
Abstract:
The invention relates to medicine and pharmacology. The novel 4,4'-biphenylamide derivatives are pharmacologically active and can be used as new effective allosteric modulators of АМРА receptors for treating Alzheimer's, Parkinson's and other neurodegenerative diseases. Also claimed are drugs for treating cognitive disorders, behavioural and mood disorders, deficit-type psychiatric disorders, attention deficit-hyperactivity disorder and other neurodegenerative diseases.

Inventors:
ZAPOLSKY, Maxim Eduardovich (ul. Serafimovicha, 6Tomilin, Moskovskaya obl. 3, 140073, RU)
ЗАПОЛЬСКИЙ, Максим Эдуардович (ул. Серафимовича, 6 Томилино, Московская обл, 3 Tomilino, 140073, RU)
ZEFIROV, Nikolay Serafimovich (Leninskiy prospekt, 99-553Moscow, 1, 119421, RU)
ЗЕФИРОВ, Николай Серафимович (Ленинский проспект, 99-553 Москва, 1 Moscow, 119421, RU)
PALYULIN, Vladimir Alexandrovich (prospekt Vernadskogo, 9/10-17Moscow, 1, 119311, RU)
ПАЛЮЛИН, Владимир Александрович (проспект Вернадского, 9/10-17 Москва, 1 Moscow, 119311, RU)
Application Number:
RU2012/000238
Publication Date:
October 11, 2012
Filing Date:
April 02, 2012
Export Citation:
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Assignee:
ZAPOLSKY, Maxim Eduardovich (ul. Serafimovicha, 6Tomilin, Moskovskaya obl. 3, 140073, RU)
ЗАПОЛЬСКИЙ, Максим Эдуардович (ул. Серафимовича, 6 Томилино, Московская обл, 3 Tomilino, 140073, RU)
ZEFIROV, Nikolay Serafimovich (Leninskiy prospekt, 99-553Moscow, 1, 119421, RU)
ЗЕФИРОВ, Николай Серафимович (Ленинский проспект, 99-553 Москва, 1 Moscow, 119421, RU)
PALYULIN, Vladimir Alexandrovich (prospekt Vernadskogo, 9/10-17Moscow, 1, 119311, RU)
ПАЛЮЛИН, Владимир Александрович (проспект Вернадского, 9/10-17 Москва, 1 Moscow, 119311, RU)
International Classes:
C07D321/10; A61K31/12; A61K31/36; A61K31/381; A61K31/40; A61K31/415; A61K31/4164; A61K31/4192; A61K31/44; A61K31/498; A61K31/4985; A61P25/28; C07D207/416; C07D213/82; C07D231/12; C07D233/64; C07D241/24; C07D241/44; C07D317/68; C07D319/18; C07D319/20; C07D333/38
Domestic Patent References:
WO2007031791A12007-03-22
WO2006110173A22006-10-19
WO2010137351A12010-12-02
Foreign References:
RU2009126653A2011-01-20
Attorney, Agent or Firm:
KORNIENKO, Elena Viktorovna (a/ya 67, Moscow, 2, 127562, RU)
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