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Title:
PHENOL DERIVATIVES AND METHOD OF USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2004/005251
Kind Code:
A1
Abstract:
Novel phenol derivatives represented by the formula (1) [wherein the carbon atom indicated by (S) is of the S configuration and Z represents the group represented by the formula (2) or the formula (3) (wherein the carbon atom indicated by (R) is of the R configuration)]. They are useful as intermediates for various medicines. Also provided is a process for producing the phenol derivative represented by the formula (A) (wherein the carbon atoms respectively indicated by (R) and (S) have the same meanings as defined above) which comprises using any of those derivatives as an intermediate therefor.

Inventors:
YAMAGUCHI TOSHIAKI (JP)
BAN MASAAKI (JP)
YANAGI TAKASHI (JP)
KIKUCHI KEN (JP)
KUBOTA MINORU (JP)
OZAWA TETSUJI (JP)
Application Number:
PCT/JP2003/008085
Publication Date:
January 15, 2004
Filing Date:
June 26, 2003
Export Citation:
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Assignee:
KISSEI PHARMACEUTICAL (JP)
YAMAGUCHI TOSHIAKI (JP)
BAN MASAAKI (JP)
YANAGI TAKASHI (JP)
KIKUCHI KEN (JP)
KUBOTA MINORU (JP)
OZAWA TETSUJI (JP)
International Classes:
C07C213/02; C07C215/60; C07D209/48; (IPC1-7): C07D209/48; C07C215/56
Foreign References:
JPS50137911A1975-11-01
US4226803A1980-10-07
GB2011389A1979-07-11
US3278600A1966-10-11
BE660217A1965-08-25
BE660218A1965-08-25
Other References:
CHEMICAL ABSTRACTS, vol. 69, 1968, Columbus, Ohio, US; abstract no. 43560, MUELLER ET AL.: "Thyronine- and thyroxine-like amino alcohols" page 4074; XP002972206
CHEMICAL ABSTRACTS, vol. 63, 1965, Columbus, Ohio, US; abstract no. 8235A-F, BECKETT ET AL.: "Configuration of alpha-methyldopamine" XP002972207
TEMPLE C. ET RENER G.A., J. MED. CHEM., vol. 35, no. 6, 1992, pages 988 - 993, XP002972208
See also references of EP 1541555A4
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