PHENYL-CYCLOALKYL AND PHENYL-HETEROCYCLIC DERIVATIVES AS S1P RECEPTOR AGONISTS

Title:

PHENYL-CYCLOALKYL AND PHENYL-HETEROCYCLIC DERIVATIVES AS S1P RECEPTOR AGONISTS

Document Type and Number:

WIPO Patent Application WO2007098474

Kind Code:

A8

Abstract:

Compounds I and II that have agonist activity at one or more of the S1P receptors are provided. The compounds are sphingosine analogs that, after phosphorylation, can behave as agonists at S1P receptors.

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Inventors:

LYNCH KEVIN R (US)
MACDONALD TIMOTHY L (US)

Application Number:

PCT/US2007/062513

Publication Date:

November 06, 2008

Filing Date:

February 21, 2007

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Assignee:

UNIV VIRGINIA (US)
LYNCH KEVIN R (US)
MACDONALD TIMOTHY L (US)

International Classes:

C07D271/06; A61P35/00; C07C251/32; C07C255/50; C07F9/02

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