Title:
PHOSPHATE-BINDING POLYMERS FOR ORAL ADMINISTRATION
Document Type and Number:
WIPO Patent Application WO1996039156
Kind Code:
A3
Abstract:
Phosphate-binding polymers are provided for removing phosphate from the gastrointestinal tract. The polymers are orally administered, and are useful for the treatment of hyperphosphatemia.
Inventors:
HOLMES-FARLEY STEPHEN RANDALL (US)
MANDEVILLE W HARRY III (US)
WHITESIDES GEORGE M (US)
MANDEVILLE W HARRY III (US)
WHITESIDES GEORGE M (US)
Application Number:
PCT/US1996/008529
Publication Date:
March 27, 1997
Filing Date:
June 03, 1996
Export Citation:
Assignee:
GELTEX PHARMA INC (US)
HOLMES FARLEY STEPHEN RANDALL (US)
MANDEVILLE W HARRY III (US)
WHITESIDES GEORGE M (US)
HOLMES FARLEY STEPHEN RANDALL (US)
MANDEVILLE W HARRY III (US)
WHITESIDES GEORGE M (US)
International Classes:
A61K9/14; A61K31/00; A61K31/785; A61K31/795; A61K45/08; A61K47/30; A61P3/00; C08F8/00; C08F20/00; C08F20/02; C08F20/52; C08F22/38; C08F26/00; C08F26/02; C08G59/40; C08G73/00; C08G73/02; C08K5/02; C08K5/09; C08K5/11; C08K5/1515; C08K5/29; C08L39/02; C08L79/02; (IPC1-7): A61K31/785
Domestic Patent References:
| WO1995005184A2 | 1995-02-23 | |||
| WO1994027621A1 | 1994-12-08 | |||
| WO1994004596A1 | 1994-03-03 |
Foreign References:
| US4071478A | 1978-01-31 | |||
| US3980770A | 1976-09-14 | |||
| NL7603653A | 1976-10-26 | |||
| EP0375350A2 | 1990-06-27 | |||
| EP0162388A1 | 1985-11-27 | |||
| FR2232563A1 | 1975-01-03 | |||
| AU480922A | 1977-02-15 |
Other References:
DATABASE CHEMABS CHEMICAL ABSTRACTS SERVICE, COLUMBUS, OHIO, US; ZABUTAYA, F. I. ET AL: "Proton NMR spectroscopic study of the reaction of epichlorohydrin with allylamine", XP002025287
DATABASE CHEMABS CHEMICAL ABSTRACTS SERVICE, COLUMBUS, OHIO, US; PETRARIU, I. ET AL: "Hofmann degradation in quaternary basic ammonium polymers I. Degradation of the linear and crosslinked basic benzylic polyelectrolytes in alkaline media", XP002025288
SHKINEV,V.M. ET AL: "Anion exchange extraction and enrichment from aqueous solutions by quaternary ammonium reagents", SOLVENT EXTRACTION AND ION EXCHANGE, vol. 7, no. 3, 1989, pages 499 - 510, XP000617752
DATABASE CHEMABS CHEMICAL ABSTRACTS SERVICE, COLUMBUS, OHIO, US; PETRARIU, I. ET AL: "Hofmann degradation in quaternary basic ammonium polymers I. Degradation of the linear and crosslinked basic benzylic polyelectrolytes in alkaline media", XP002025288
SHKINEV,V.M. ET AL: "Anion exchange extraction and enrichment from aqueous solutions by quaternary ammonium reagents", SOLVENT EXTRACTION AND ION EXCHANGE, vol. 7, no. 3, 1989, pages 499 - 510, XP000617752
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