Title:
PHOSPHATIDATE PHOSPHATASE GENE AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2011/081135
Kind Code:
A1
Abstract:
Disclosed is a novel phosphatidate phosphatase gene.
Specifically disclosed are: a nucleotide sequence represented by SEQ ID NO: 1 or SEQ ID NO: 7, SEQ ID NO: 4 or SEQ ID NO: 9, or SEQ ID NO: 5 or SEQ ID NO: 10; and an amino acid sequence represented by SEQ ID NO: 2 or SEQ ID NO: 6.
Inventors:
OCHIAI MISA (JP)
Application Number:
PCT/JP2010/073565
Publication Date:
July 07, 2011
Filing Date:
December 27, 2010
Export Citation:
Assignee:
SUNTORY HOLDINGS LTD (JP)
OCHIAI MISA (JP)
OCHIAI MISA (JP)
International Classes:
C12N15/00; A23L1/30; C12N1/15; C12N1/19; C12N1/21; C12N5/10; C12N9/16; C12N15/09; C12P7/64
Domestic Patent References:
| WO2009008466A1 | 2009-01-15 | |||
| WO2009008466A1 | 2009-01-15 | |||
| WO2001040514A1 | 2001-06-07 |
Foreign References:
| JPH08205900A | 1996-08-13 | |||
| JP2001120276A | 2001-05-08 |
Other References:
MORIHISA FUJITA ET AL.: "Shishitsu Chikusekisei Biseibutsu ni Okeru Kayosei Phosphatidate-san Phosphatase no Kaiseki to Seisei", DAI 75 KAI ANNUAL MEETING OF THE JAPANESE BIOCHEMICAL SOCIETY HAPPYO SHOROKUSHU, 2002, pages 970(4P-013), XP008161133
CARMAN GM. ET AL.: "Phosphatidate phosphatases and diacylglycerol pyrophosphate phosphatases in Saccharomyces cerevisiae and Escherichia coli.", BIOCHIM BIOPHYS ACTA., vol. 1348, no. 1-2, 1997, pages 45 - 55, XP008161132
HAN GS ET AL.: "The Saccharomyces cerevisiae Lipin homolog is a Mg2+-dependent phosphatidate phosphatase enzyme.", J BIOL CHEM., vol. 281, no. 14, 2006, pages 9210 - 9218, XP008161130
CARMAN GM ET AL.: "Roles of phosphatidate phosphatase enzymes in lipid metabolism.", TRENDS BIOCHEM SCI., vol. 31, no. 12, 2006, pages 694 - 699, XP025132570, DOI: doi:10.1016/j.tibs.2006.10.003
BIOCHEM. BIOPHYS. ACTA, vol. 1348, 1997, pages 45 - 55
TRENDS BIOCHEM. SCI., vol. 31, no. 12, 2006, pages 694 - 699
EMBO J., vol. 24, 2005, pages 1931 - 1941
J. BIOL. CHEM., vol. 281, no. 14, 2006, pages 9210 - 9218
J. BIOL. CHEM., vol. 281, no. 45, 2006, pages 34537 - 34548
J. BIOL. CHEM., vol. 282, no. 51, 2007, pages 37026 - 37035
J. BIOL. CHEM., vol. 284, no. 5, 2009, pages 2593 - 2597
"Molecular Cloning, A Laboratory Manual", 2001, COLD SPRING HARBOR PRESS
KYTE ET AL., J. MOL.BIOL., vol. 157, 1982, pages 105 - 131
"Immunology--A Synthesis", 1991, SINAUER ASSOCIATES
"Current Protocols in Molecular Biology", 1987, JOHN WILEY & SONS
KUNKEL, PROC. NATL. ACAD. SCI. USA, vol. 82, 1985, pages 488 - 92
KUNKEL, METHOD ENZYMOL., vol. 85, 1988, pages 2763 - 6
J. BID. CHEM., vol. 273, 1998, pages 14331 - 14338
"DNA Cloning 1: Core Techniques, A Practical Approach", 1995
ALTSCHUL ET AL., J. MOL. BIOL., vol. 215, 1990, pages 403 - 10
ALTSCHUL ET AL., J. MOL. BIOL., vol. 215, 1990, pages 403 - 410
ALTSCHUL ET AL., NUCL. ACIDS. RES., vol. 25, 1997, pages 3389 - 3402
WOOTTON; FEDERHEN, COMPUTERS AND CHEMISTRY, 1993
WOOTTON; FEDERHEN: "Analysis of compositionally biased regions in sequence databases", METHODS ENZYMOL., vol. 266, 1996, pages 554 - 71
COMPUTERS AND CHEMISTRY, 1993
MYCOTAXON, vol. XLIV, no. 2, 1992, pages 257 - 265
"Methods in Yeast Genetics", 1990, COLD SPRING HARBOR LABORATORY PRESS, pages: 130
"Current Protocols in Molecular Biology", 1994, JOHN WILEY & SONS
"Biochemistry Experiments vol. 39, Experimental Protocols for Yeast Molecular Genetics", vol. 39, JAPAN SCIENTIFIC SOCIETIES PRESS, pages: 67 - 75
BIOSCI. BIOTECH. BIOCHEM., vol. 59, 1995, pages 1221 - 1228
GIL-SOO ET AL., J. BIOL. CHEM., vol. 282, no. 51, 2007, pages 37026 - 37035
CARMAN GM. ET AL.: "Phosphatidate phosphatases and diacylglycerol pyrophosphate phosphatases in Saccharomyces cerevisiae and Escherichia coli.", BIOCHIM BIOPHYS ACTA., vol. 1348, no. 1-2, 1997, pages 45 - 55, XP008161132
HAN GS ET AL.: "The Saccharomyces cerevisiae Lipin homolog is a Mg2+-dependent phosphatidate phosphatase enzyme.", J BIOL CHEM., vol. 281, no. 14, 2006, pages 9210 - 9218, XP008161130
CARMAN GM ET AL.: "Roles of phosphatidate phosphatase enzymes in lipid metabolism.", TRENDS BIOCHEM SCI., vol. 31, no. 12, 2006, pages 694 - 699, XP025132570, DOI: doi:10.1016/j.tibs.2006.10.003
BIOCHEM. BIOPHYS. ACTA, vol. 1348, 1997, pages 45 - 55
TRENDS BIOCHEM. SCI., vol. 31, no. 12, 2006, pages 694 - 699
EMBO J., vol. 24, 2005, pages 1931 - 1941
J. BIOL. CHEM., vol. 281, no. 14, 2006, pages 9210 - 9218
J. BIOL. CHEM., vol. 281, no. 45, 2006, pages 34537 - 34548
J. BIOL. CHEM., vol. 282, no. 51, 2007, pages 37026 - 37035
J. BIOL. CHEM., vol. 284, no. 5, 2009, pages 2593 - 2597
"Molecular Cloning, A Laboratory Manual", 2001, COLD SPRING HARBOR PRESS
KYTE ET AL., J. MOL.BIOL., vol. 157, 1982, pages 105 - 131
"Immunology--A Synthesis", 1991, SINAUER ASSOCIATES
"Current Protocols in Molecular Biology", 1987, JOHN WILEY & SONS
KUNKEL, PROC. NATL. ACAD. SCI. USA, vol. 82, 1985, pages 488 - 92
KUNKEL, METHOD ENZYMOL., vol. 85, 1988, pages 2763 - 6
J. BID. CHEM., vol. 273, 1998, pages 14331 - 14338
"DNA Cloning 1: Core Techniques, A Practical Approach", 1995
ALTSCHUL ET AL., J. MOL. BIOL., vol. 215, 1990, pages 403 - 10
ALTSCHUL ET AL., J. MOL. BIOL., vol. 215, 1990, pages 403 - 410
ALTSCHUL ET AL., NUCL. ACIDS. RES., vol. 25, 1997, pages 3389 - 3402
WOOTTON; FEDERHEN, COMPUTERS AND CHEMISTRY, 1993
WOOTTON; FEDERHEN: "Analysis of compositionally biased regions in sequence databases", METHODS ENZYMOL., vol. 266, 1996, pages 554 - 71
COMPUTERS AND CHEMISTRY, 1993
MYCOTAXON, vol. XLIV, no. 2, 1992, pages 257 - 265
"Methods in Yeast Genetics", 1990, COLD SPRING HARBOR LABORATORY PRESS, pages: 130
"Current Protocols in Molecular Biology", 1994, JOHN WILEY & SONS
"Biochemistry Experiments vol. 39, Experimental Protocols for Yeast Molecular Genetics", vol. 39, JAPAN SCIENTIFIC SOCIETIES PRESS, pages: 67 - 75
BIOSCI. BIOTECH. BIOCHEM., vol. 59, 1995, pages 1221 - 1228
GIL-SOO ET AL., J. BIOL. CHEM., vol. 282, no. 51, 2007, pages 37026 - 37035
Attorney, Agent or Firm:
ONO, Shinjiro et al. (JP)
Ono Shinjiro (JP)
Ono Shinjiro (JP)
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