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Title:
PHOSPHORUS-CONTAINING PYRIDO PYRIMIDONE COMPOUND OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF, PHARMACEUTICAL COMPOSITION AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2016/023401
Kind Code:
A1
Abstract:
Provided is a phosphorus-containing pyrido [2, 3-d] pyrimide-7-ketone compound as represented by formula (I) or a pharmaceutically acceptable salt thereof. Also disclosed are a preparation method of the compound, a pharmaceutical composition comprising the phosphorus-containing pyrido [2, 3-d] pyrimide-7-ketone compound and a use thereof. The compound is a protein kinase (for example PI3K) inhibitor capable of treating diseases caused by abnormal activity of the protein kinase, such as a tumor.

Inventors:
LV HUIMIN (CN)
Application Number:
PCT/CN2015/081854
Publication Date:
February 18, 2016
Filing Date:
June 18, 2015
Export Citation:
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Assignee:
SHANDONG HUIRUIDI BIOTECHNOLOGY CO LTD (CN)
International Classes:
C07F9/6561; A61K31/675; A61P1/16; A61P3/10; A61P9/00; A61P11/00; A61P17/06; A61P19/02; A61P25/08; A61P25/14; A61P25/16; A61P25/28; A61P29/00; A61P35/00; A61P35/02; A61P37/02
Domestic Patent References:
WO2013043232A22013-03-28
WO2012148540A12012-11-01
Foreign References:
CN101573358A2009-11-04
Attorney, Agent or Firm:
CN-KNOWHOW INTELLECTUAL PROPERTY AGENT LIMITED (CN)
北京路浩知识产权代理有限公司 (CN)
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