Title:
PHOTOCROSSLINKED HYDROGEL SURFACE COATINGS
Document Type and Number:
WIPO Patent Application WO2004076511
Kind Code:
A3
Abstract:
A hydrogel layer is applied to a substrate advantageously when the layer is formed in situ, using a polymeric or copolymeric precursor that includes, respectively, monomer subunits that have a photocrosslinkable functionality and monomer subunits that have a chemically selective functionality for binding a biomolecular analyte, such as a protein. A hydrogel-coated substrate thus obtained is particularly useful as a probe for mass spectroscopic analysis, including SELDI analysis. Hydrogel particles also can be used for SELDI analysis.
Inventors:
HUANG WENXI (US)
AGROSKIN YURY (US)
BOSCHETTI EGISTO (FR)
AGROSKIN YURY (US)
BOSCHETTI EGISTO (FR)
Application Number:
PCT/US2004/004847
Publication Date:
December 16, 2004
Filing Date:
February 20, 2004
Export Citation:
Assignee:
CIPHERGEN BIOSYSTEMS INC (US)
HUANG WENXI (US)
AGROSKIN YURY (US)
BOSCHETTI EGISTO (FR)
HUANG WENXI (US)
AGROSKIN YURY (US)
BOSCHETTI EGISTO (FR)
International Classes:
A61L27/00; C08F290/00; C08J7/16; G01N33/543; C08G; (IPC1-7): G01N33/543; C08J7/16; C08F290/00; A61L27/00
Domestic Patent References:
| WO2000066265A2 | 2000-11-09 | |||
| WO2001067129A2 | 2001-09-13 | |||
| WO2000040593A2 | 2000-07-13 | |||
| WO2002100453A1 | 2002-12-19 | |||
| WO2003093785A2 | 2003-11-13 | |||
| WO2004024318A1 | 2004-03-25 |
Foreign References:
| US6410643B1 | 2002-06-25 | |||
| US5858653A | 1999-01-12 | |||
| GB2171106A | 1986-08-20 |
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