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Title:
PHOTONIC INACTIVATION OF PATHOGENS
Document Type and Number:
WIPO Patent Application WO/2018/222856
Kind Code:
A3
Abstract:
Devices, systems and methods for the inactivation of pathogens such as viruses in a liquid medium containing products such as pharmaceutical compounds are presented. These are useful, for example, for the inactivation of viruses in liquids containing antibody pharmaceuticals, and make use of one or more of flow-through inactivation, plasmonic virus inactivation enhancement, mode matching between hydrodynamic flow profile and laser intensity profile, and nonlinear flow geometries. The methods allow flow-through pathogen inactivation while avoiding collateral damage to products to be decontaminated.

Inventors:
ASHER, Damon, R. (400 Summit Drive, Burlington, MA, 01803, US)
ERRAMILLI, Shyamsunder (41 Village Drive, Quincy, MA, 02169, US)
GAGNE, George (400 Summit Drive, Burlington, MA, 01803, US)
GILLESPIE, Christopher (400 Summit Drive, Burlington, MA, 01803, US)
GUMMULURU, Suryaram (9 Phillips Brooks Rd, Westwood, MA, 02090, US)
HONG, Mi, Kyung (89 Village Dr, Quincy, MA, 02169, US)
MIURA, Ayako (400 Summit Drive, Burlington, MA, 01803, US)
NAZARI, Mina, N. (179 Brookline Ave, Unit 219Boston, MA, 02215, US)
REINHARD, Bjoern (12 Glenwood Ave, Newton, MA, 02459, US)
SOUZA, Kathleen (400 Summit Drive, Burlington, MA, 01803, US)
XI, Min (185 Freeman St. Apt 643, Brookline, MA, 02446, US)
Application Number:
US2018/035369
Publication Date:
January 17, 2019
Filing Date:
May 31, 2018
Export Citation:
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Assignee:
EMD MILLIPORE CORPORATION (400 Summit Drive, Burlington, MA, 01803, US)
TRUSTEES OF BOSTON UNIVERSITY (One Silber Way, Boston, MA, 02215, US)
International Classes:
A23L3/26; A61L2/00; A61L2/08; A61M1/36; C02F1/30
Foreign References:
US20140272030A12014-09-18
Other References:
XUEXIANG HU ET AL: "Plasmon-Induced Inactivation of Enteric Pathogenic Microorganisms with Ag-AgI/Al 2 O 3 under Visible-Light Irradiation", ENVIRONMENTAL SCIENCE & TECHNOLOGY, vol. 44, no. 18, 15 September 2010 (2010-09-15), US, pages 7058 - 7062, XP055509108, ISSN: 0013-936X, DOI: 10.1021/es1012577
Attorney, Agent or Firm:
CARROLL, Alice, O. et al. (Hamilton, Brook Smith & Reynolds, P.C.,530 Virginia Rd, P.O. Box 913, Concord MA, 01742-9133, US)
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